Anti-STXBP2 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-STXBP2 Antibody (CSB-PA618999ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Syntaxin-binding protein 2 Antibody,Protein unc-18 homolog 2 Antibody,Unc18-2 Antibody,Protein unc-18 homolog B Antibody,Unc-18B Antibody,STXBP2 Antibody,UNC18B Antibody

More alternative names for the antibody
FHL5 antibody|Hunc18b antibody|MUNC18 2 antibody|pp10122 antibody|Protein unc-18 homolog 2 antibody|Protein unc-18 homolog B antibody|STXB2_HUMAN antibody|Stxbp2 antibody|syntaxin binding protein 2 antibody|Syntaxin-binding protein 2 antibody|Unc-18B antibody|UNC18 2 antibody|Unc18-2 antibody|UNC18B antibody
Anti-STXBP2 antibody (ab103976)
Close

Recommended applications: ELISA, WB

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-STXBP2 Antibody

Catalogue No.

CSB-PA618999ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Syntaxin-binding protein 2 protein (1-280AA)

Host

Rabbit

Applications

ELISA, WB

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

66 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:515618( Cow), Entrez Gene:403880( Dog), Entrez Gene:6813( Human), Entrez Gene:20911( Mouse), Entrez Gene:81804( Rat), Omim:601717( Human), SwissProt:Q28288( Dog), SwissProt:Q15833( Human), SwissProt:Q64324( Mouse), SwissProt:Q62753( Rat), Unigene:515104( Human), Unigene:7247( Mouse), Unigene:10121( Rat)

Protein function

Involved in intracellular vesicle trafficking and vesicle fusion with membranes. Contributes to the granule exocytosis machinery through interaction with soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins that regulate membrane fusion. Regulates cytotoxic granule exocytosis in natural killer (NK) cells. .

Protein tissue specificity

Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.

Involvement in disease

Familial hemophagocytic lymphohistiocytosis 5 (FHL5) [MIM:613101]: A rare disorder characterized by immune dysregulation with hypercytokinemia, defective function of natural killer cell, and massive infiltration of several organs by activated lymphocytes and macrophages. The clinical features of the disease include fever, hepatosplenomegaly, cytopenia, and less frequently neurological abnormalities ranging from irritability and hypotonia to seizures, cranial nerve deficits and ataxia. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the STXBP/unc-18/SEC1 family.

Research area

All research areas>Neurobiology Antibodies>Unc
(View all antibody categories related to Neurobiology Antibodies)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!