Anti-SUCLA2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-SUCLA2 Antibody (CSB-PA868398ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Succinyl-CoA ligase [ADP-forming] subunit beta Antibody,mitochondrial Antibody,ATP-specific succinyl-CoA synthetase subunit beta Antibody,Renal carcinoma antigen NY-REN-39 Antibody,Succinyl-CoA synthetase beta-A chain Antibody,SCS-betaA Antibody,SUCLA2 Antibody

More alternative names for the antibody
ATP specific succinyl CoA synthetase subunit beta antibody|ATP-specific succinyl-CoA synthetase subunit beta antibody|Renal carcinoma antigen NY-REN-39 antibody|Renal carcinoma antigen NYREN39 antibody|SCS betaA antibody|SCS-betaA antibody|SUCB1_HUMAN antibody|Succinate CoA ligase ADP forming beta subunit antibody|Succinyl CoA ligase [ADP-forming] subunit beta, mitochondrial antibody|Succinyl CoA synthetase beta A chain antibody|Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial antibody|Succinyl-CoA synthetase beta-A chain antibody|SUCLA2 antibody
Anti-SUCLA2 antibody [EPR14924] (ab202582)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-SUCLA2 Antibody

Catalogue No.

CSB-PA868398ESR1HU

Reactivity

Human

Immunogen

Recombinant human Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial protein (1-180AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

50 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8803( Human), Entrez Gene:20916( Mouse), Entrez Gene:361071( Rat), Omim:603921( Human), SwissProt:Q9P2R7( Human), SwissProt:Q9Z2I9( Mouse), SwissProt:B2RZ24( Rat), Unigene:743361( Human), Unigene:38951( Mouse)

Protein function

ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA (PubMed:15877282). The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit (By similarity). .

Protein tissue specificity

Widely expressed. Not expressed in liver and lung. .

Involvement in disease

Mitochondrial DNA depletion syndrome 5 (MTDPS5) [MIM:612073]: A disorder due to mitochondrial dysfunction. It is characterized by infantile onset of hypotonia, neurologic deterioration, a hyperkinetic-dystonic movement disorder, external ophthalmoplegia, deafness, variable renal tubular dysfunction, and mild methylmalonic aciduria in some patients. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the succinate/malate CoA ligase beta subunit family. ATP-specific subunit beta subfamily.

Protein cellular localization

Mitochondrion .

Research area

All research areas>Synthesis and Degradation>SUCLA
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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