Anti-TAF1B Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TAF1B Antibody (CSB-PA684476ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

RNA polymerase I-specific TBP-associated factor 63 kDa Antibody,TAFI63 Antibody,TATA box-binding protein-associated factor 1B Antibody,TBP-associated factor 1B Antibody,Transcription initiation factor SL1/TIF-IB subunit B Antibody,TAF1B Antibody

More alternative names for the antibody
MGC:9349 antibody|OTTHUMP00000200348 antibody|RAF1B antibody|RAFI63 antibody|RNA polymerase I-specific TBP-associated factor 63 kDa antibody|SL1 antibody|SL1, 63kD subunit antibody|Taf1b antibody|TAF1B_HUMAN antibody|TAFI63 antibody|TATA box-binding protein-associated factor 1B antibody|TATA box-binding protein-associated factor RNA polymerase I subunit B antibody|TBP-associated factor 1B antibody|Transcription initiation factor SL1/TIF-IB subunit B antibody
Anti-TAF1B antibody (ab90549)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TAF1B Antibody

Catalogue No.

CSB-PA684476ESR1HU

Reactivity

Human

Immunogen

Recombinant human TATA box-binding protein-associated factor RNA polymerase I subunit B protein (369-588AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

68 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene: 9014( Human), Omim:604904( Human), SwissProt:Q53T94( Human)

Protein function

Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3. .

Protein sequence and domain

Belongs to the RRN7/TAF1B family. Although it shares weak sequence similarity with GTF2B/TFIIB, displays a similar subdomain organization as GTF2B/TFIIB, with a N-terminal zinc finger, a connecting region (composed of B-reader and B-linker regions), followed by 2 cyclin folds. The RRN7-type zinc finger plays an essential postrecruitment role in Pol I transcription at a step preceding synthesis of the first 40 nucleotides (PubMed:21921198 and PubMed:21921199).

Protein cellular localization

Nucleus, nucleolus.

Research area

All research areas>Transcription Regulators>TAF Basal Transcription Factor
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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