Anti-TARBP2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TARBP2 Antibody (CSB-PA623007ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

TAR RNA-binding protein 2 Antibody,Trans-activation-responsive RNA-binding protein Antibody,TARBP2 Antibody,TRBP Antibody

More alternative names for the antibody
LOQS antibody|Prbp antibody|RISC loading complex subunit TARBP2 antibody|RISC-loading complex subunit tarbp2 antibody|TAR (HIV 1) RNA binding protein 2 antibody|TAR (HIV) RNA binding protein 2 antibody|TAR (HIV) RNA-binding protein TRBP1 antibody|TAR RNA Binding Protein 2 antibody|TAR RNA-binding protein 2 antibody|tarbp2 antibody|TARBP2 RISC loading complex RNA binding subunit antibody|Trans-activation-responsive RNA-binding protein antibody|TRBP antibody|TRBP1 antibody|TRBP2 antibody|TRBP2_HUMAN antibody
Anti-TRBP antibody [EPR13550] (ab180947)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TARBP2 Antibody

Catalogue No.

CSB-PA623007ESR1HU

Reactivity

Human

Immunogen

Recombinant human RISC-loading complex subunit TARBP2 protein (1-366AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

39 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:6895( Human), Entrez Gene:21357( Mouse), Entrez Gene:363006( Rat), Omim:605053( Human), SwissProt:Q15633( Human), SwissProt:P97473( Mouse), SwissProt:Q3SWU0( Rat), Unigene:326( Human), Unigene:291485( Mouse), Unigene:17227( Rat)

Protein function

Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. This is achieved in part at least by binding to and inhibiting EIF2AK2/PKR, thereby reducing phosphorylation and inhibition of EIF2S1/eIF-2-alpha. May also promote translation of TAR-containing RNAs independently of EIF2AK2/PKR. .

Protein sequence and domain

Belongs to the TARBP2 family.

Protein cellular localization

Cytoplasm. Cytoplasm, perinuclear region. Nucleus.

Research area

All research areas>Steroid Receptors>TRBP
(View all antibody categories related to Steroid Receptors)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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