Anti-TBL1XR1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TBL1XR1 Antibody (CSB-PA883647ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Nuclear receptor corepressor/HDAC3 complex subunit TBLR1 Antibody,TBL1-related protein 1 Antibody,Transducin beta-like 1X-related protein 1 Antibody,TBL1XR1 Antibody,IRA1 Antibody,TBLR1 Antibody

More alternative names for the antibody
C21 antibody|
Anti-TBLR1 antibody – ChIP Grade (ab24550)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TBL1XR1 Antibody

Catalogue No.

CSB-PA883647ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human F-box-like/WD repeat-containing protein TBL1XR1 protein (1-180AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

55 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:79718( Human), Omim:608628( Human), SwissProt:Q9BZK7( Human), Unigene:581171( Human)

Protein function

F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of N-Cor complex, thereby allowing cofactor exchange, and transcription activation. .

Protein tissue specificity

Widely expressed including the pituitary, hypothalamus, white and brown adipose tissue, muscle and liver. .

Involvement in disease

Pierpont syndrome (PRPTS) [MIM:602342]: An autosomal dominant syndrome characterized by multiple congenital anomalies, global developmental delay, learning disability, palmar and plantar fat pads, and distinctive facial characteristics, especially when smiling. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Mental retardation, autosomal dominant 41 (MRD41) [MIM:616944]: A form of mental retardation, a disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRD41 patients manifest delayed psychomotor development, variable severity of intellectual disability, and delayed language. Non-specific dysmorphic features and autistic behavior is observed in some patients. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the WD repeat EBI family. The F-box-like domain is related to the F-box domain, and apparently displays the same function as component of ubiquitin E3 ligase complexes.

Protein cellular localization

Nucleus .

Research area

All research areas>Steroid Receptors>TBL
(View all antibody categories related to Steroid Receptors)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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