Anti-TCEB2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TCEB2 Antibody (CSB-PA620878ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Elongin 18 kDa subunit Antibody,Elongin-B Antibody, EloB Antibody,RNA polymerase II transcription factor SIII subunit B Antibody,SIII p18 Antibody,TCEB2 Antibody

More alternative names for the antibody
EloB antibody|ELOB_HUMAN antibody|Elongin 18 kDa subunit antibody|Elongin B antibody|Elongin-B antibody|RNA polymerase II transcription factor SIII p18 subunit antibody|RNA polymerase II transcription factor SIII subunit B antibody|SIII antibody|SIII p18 antibody|TCEB 2 antibody|Tceb2 antibody|Transcription elongation factor B (SIII) polypeptide 2 antibody|Transcription elongation factor B polypeptide 2 antibody
Anti-TCEB2 antibody (ab168836)
Close sc-133090|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TCEB2 Antibody

Catalogue No.

CSB-PA620878ESR1HU

Reactivity

Human

Immunogen

Recombinant human Transcription elongation factor B polypeptide 2 protein (1-118AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

13 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:750134( Chimpanzee), Entrez Gene:617277( Cow), Entrez Gene:479873( Dog), Entrez Gene:100861051( Goat), Entrez Gene:6923( Human), Entrez Gene:67673( Mouse), Entrez Gene:715218( Rhesus monkey), Omim:600787( Human), SwissProt:Q15370( Human), SwissProt:P62869( Mouse), Unigene:172772( Human), Unigene:153758( Mouse)

Protein function

SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex) (PubMed:7638163). In embryonic stem cells, the elongin BC complex is recruited by EPOP to Polycomb group (PcG) target genes in order generate genomic region that display both active and repressive chromatin properties, an important feature of pluripotent stem cells (By similarity). .; The elongin BC complex seems to be involved as an adapter protein in the proteasomal degradation of target proteins via different E3 ubiquitin ligase complexes, including the von Hippel-Lindau ubiquitination complex CBC(VHL). By binding to BC-box motifs it seems to link target recruitment subunits, like VHL and members of the SOCS box family, to Cullin/RBX1 modules that activate E2 ubiquitination enzymes. .

Protein cellular localization

Nucleus .

Research area

All research areas>Tumor Suppressor/Apoptosis>Elongin
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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