Anti-TCTN2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TCTN2 Antibody (CSB-PA853425ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

TCTN2 Antibody,C12orf38 Antibody,TECT2 Antibody

More alternative names for the antibody
C12orf38 antibody|FLJ12975 antibody|MKS8 antibody|OTTHUMP00000239215 antibody|OTTHUMP00000239216 antibody|Tctn2 antibody|TECT2 antibody|TECT2_HUMAN antibody|Tectonic family member 2 antibody|Tectonic-2 antibody
Anti-TCTN2 antibody (ab117621)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TCTN2 Antibody

Catalogue No.

CSB-PA853425ESR1HU

Reactivity

Human

Immunogen

Recombinant human Tectonic-2 protein (420-670AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

76 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:79867( Human), Entrez Gene:67978( Mouse), Omim:613846( Human), SwissProt:Q96GX1( Human), SwissProt:Q2MV57( Mouse), Unigene:167165( Human), Unigene:93193( Mouse)

Protein function

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for hedgehog signaling transduction (By similarity). .

Involvement in disease

Meckel syndrome 8 (MKS8) [MIM:613885]: A disorder characterized by a combination of renal cysts and variably associated features including developmental anomalies of the central nervous system (typically encephalocele), hepatic ductal dysplasia and cysts, and polydactyly. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Joubert syndrome 24 (JBTS24) [MIM:616654]: A form of Joubert syndrome, a disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermian hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy, renal disease, liver fibrosis, and polydactyly. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the tectonic family.

Protein cellular localization

Membrane ; Single-pass type I membrane protein . Cytoplasm, cytoskeleton, cilium basal body . Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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