Anti-TFDP1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TFDP1 Antibody (CSB-PA023424ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

DRTF1-polypeptide 1 Antibody,DRTF1 Antibody,E2F dimerization partner 1 Antibody,TFDP1 Antibody,DP1 Antibody

More alternative names for the antibody
DP 1 antibody|TFDP1 antibody|TFDP1_HUMAN antibody|Transcription factor Dp-1 antibody|Transcription factor sequence-specific, DRTF1 antibody
Anti-DP1 antibody – C-terminal (ab208945)
Close sc-70990|sc-70989|sc-610|sc-56526|sc-53642|sc-56657|sc-393398|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TFDP1 Antibody

Catalogue No.

CSB-PA023424ESR2HU

Reactivity

Human

Immunogen

Recombinant human Transcription factor Dp-1 protein (1-290AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

45 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:7027( Human), Entrez Gene:21781( Mouse), Entrez Gene:361178( Rat), Omim:189902( Human), SwissProt:Q14186( Human), SwissProt:Q08639( Mouse), Unigene:79353( Human), Unigene:925( Mouse), Unigene:13772( Rat)

Protein function

Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5′-TTTC[CG]CGC-3′, found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The E2F1:DP complex appears to mediate both cell proliferation and apoptosis. Blocks adipocyte differentiation by repressing CEBPA binding to its target gene promoters (PubMed:20176812). .

Protein tissue specificity

Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart.

Protein sequence and domain

Belongs to the E2F/DP family.

Protein post-translational modifications

Phosphorylation by E2F1-bound cyclin A-CDK2, in the S phase, inhibits E2F-mediated DNA binding and transactivation. .

Protein cellular localization

Nucleus.

Research area

All research areas>Transcription Regulators>Dimerization Partner
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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