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Rabbit Anti-TGS1 Antibody (CSB-PA847219ESR1HU)
Supplier: CUSABIO BIOTECH CO.
CLL-associated antigen KW-2 Antibody,Cap-specific guanine-N2 methyltransferase Antibody,Hepatocellular carcinoma-associated antigen 137 Antibody,Nuclear receptor coactivator 6-interacting protein Antibody,PRIP-interacting protein with methyltransferase motif Antibody,PIMT Antibody,PIPMT Antibody,TGS1 Antibody,HCA137 Antibody, NCOA6IP Antibody,PIMT AntibodyMore alternative names for the antibody
Cap specific guanine N2 methyltransferase antibody|Cap-specific guanine-N2 methyltransferase antibody|CLL associated antigen KW 2 antibody|CLL-associated antigen KW-2 antibody|DKFZp762A163 antibody|FLJ22995 antibody|HCA137 antibody|Hepatocellular carcinoma associated antigen 137 antibody|Hepatocellular carcinoma-associated antigen 137 antibody|NCOA6IP antibody|Nuclear receptor coactivator 6 interacting protein antibody|Nuclear receptor coactivator 6-interacting protein antibody|PIMT antibody|PIPMT antibody|PRIP interacting protein PIPMT antibody|PRIP interacting protein with methyltransferase domain antibody|PRIP interacting protein with methyltransferase motif antibody|PRIP-interacting protein with methyltransferase motif antibody|SEREX defined antibody|TGS 1 antibody|Tgs1 antibody|TGS1_HUMAN antibody|Trimethylguanosine synthase antibody|Trimethylguanosine synthase homolog (S. cerevisiae) antibody|Trimethylguanosine synthase homolog antibody
Anti-PIMT antibody (ab70559)
Anti-PIMT antibody (ab70559)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Trimethylguanosine synthase protein (714-853AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=96764" target="_blank">Entrez Gene:96764( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/606461" target="_blank">Omim:606461( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q96RS0" target="_blank">SwissProt:Q96RS0( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=335068" target="_blank">Unigene:335068( Human)</a>
|Protein function|| |
Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m(7)G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation. .
|Protein tissue specificity|| |
Ubiquitously expressed. High expression in heart, skeletal muscle, kidney, liver and placenta. .
|Protein sequence and domain|| |
Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.
|Protein cellular localization|| |
Cytoplasm . Nucleus, Cajal body . Nucleus, nucleolus . Note=A 90 kDa isoform is found in the nucleus while a 55 kDa isoform is found in the cytoplasm and colocalizes with the tubulin network. .
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Transcription-Regulators/">Transcription Regulators</a>><a href="https://antibodyplus.com/product-tag/PIMT/">PIMT</a><br><a href="https://antibodyplus.com/product-tag/Transcription-Regulators/"> (View all antibody categories related to Transcription Regulators)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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