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Rabbit Anti-TMED10 Antibody (CSB-PA023655ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Transmembrane emp24 domain-containing protein 10 Antibody,21 kDa transmembrane-trafficking protein Antibody,S31III125 Antibody,S31I125 Antibody,Tmp-21-I Antibody,Transmembrane protein Tmp21 Antibody,p23 Antibody,p24 family protein delta-1 Antibody,p24delta1 Antibody,p24delta Antibody,TMED10 Antibody,TMP21 AntibodyMore alternative names for the antibody
1110014C03Rik antibody|21 kDa transmembrane trafficking protein antibody|21 kDa transmembrane-trafficking protein antibody|MGC102351 antibody|p23 antibody|p24 family protein delta 1 antibody|p24 family protein delta-1 antibody|p24(DELTA) antibody|p24delta antibody|p24delta1 antibody|S31I125 antibody|S31III125 antibody|TMED 10 antibody|Tmed10 antibody|TMEDA_HUMAN antibody|Tmp 21 I antibody|Tmp 21 antibody|Tmp 21 I antibody|Tmp-21-I antibody|Transmembrane emp24 domain containing protein 10 antibody|Transmembrane emp24 domain-containing protein 10 antibody|Transmembrane emp24-like trafficking protein 10 (yeast) antibody|Transmembrane protein Tmp21 antibody|Transmembrane trafficking protein 21kD antibody
Anti-TMP21 antibody – C-terminal (ab189088)
Anti-TMP21 antibody – C-terminal (ab189088)
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Transmembrane emp24 domain-containing protein 10 protein (35-190AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:10972( Human), Entrez Gene:68581( Mouse), Entrez Gene:84599( Rat), Omim:605406( Human), SwissProt:P49755( Human), SwissProt:Q9D1D4( Mouse), SwissProt:Q63584( Rat), Unigene:74137( Human), Unigene:379159( Mouse), Unigene:472063( Mouse), Unigene:8509( Rat)
|Protein function|| |
Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft-like microdomains of the ER. Recognizes GPI anchors structural remodeled in the ER by PGAP1 and MPPE1 (By similarity). In COPI vesicle-mediated retrograde transport involved in the biogenesis of COPI vesicles and vesicle coat recruitment. On Golgi membranes, acts as primary receptor for ARF1-GDP which is involved in COPI-vesicle formation. Increases coatomer-dependent GTPase-activating activity of ARFGAP2. Involved in trafficking of G protein-coupled receptors (GPCRs). Regulates F2LR1, OPRM1 and P2RY4 exocytic trafficking from the Golgi to the plasma membrane thus contributing to receptor resensitization. Involved in trafficking of amyloid beta A4 protein and soluble APP-beta release (independent of modulation of gamma-secretase activity). As part of the presenilin-dependent gamma-secretase complex regulates gamma-cleavages of the amyloid beta A4 protein to yield amyloid-beta 40 (Abeta40). Involved in organization of the Golgi apparatus. .
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Belongs to the EMP24/GP25L family. The lumenal domain mediates localization to the plasma membrane by partially overriding the ER retention by the cytoplasmic domain.
|Protein cellular localization|| |
Golgi apparatus, cis-Golgi network membrane; Single-pass type I membrane protein. Melanosome. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle membrane ; Single-pass type I membrane protein . Cell membrane . Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein . Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Cycles between compartments of the early secretatory pathway.
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CUSABIO BIOTECH CO.
|Product type|| |
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