Anti-TMEFF2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TMEFF2 Antibody (CSB-PA883439ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Tomoregulin-2 Antibody,TR-2 Antibody,Hyperplastic polyposis protein 1 Antibody,Transmembrane protein with EGF-like and two follistatin-like domains Antibody,TMEFF2 Antibody,HPP1 Antibody,TENB2 Antibody,TPEF Antibody,UNQ178/PRO204 Antibody

More alternative names for the antibody
Cancer/testis antigen family 120 member 2 antibody|CT120.2 antibody|HPP 1 antibody|HPP1 antibody|Hyperplastic polyposis protein 1 antibody|TEFF 2 antibody|TEFF2 antibody|TEFF2_HUMAN antibody|TENB 2 antibody|TENB2 antibody|TMEFF2 antibody|Tomoregulin antibody|Tomoregulin-2 antibody|TPEF antibody|TR 2 antibody|TR antibody|TR-2 antibody|Transmembrane protein containing epidermal growth factor and follistatin domains antibody|Transmembrane protein TENB2 antibody|Transmembrane protein with EGF like and two follistatin like domains 2 antibody|Transmembrane protein with EGF-like and two follistatin-like domains antibody
Anti-TMEFF2 antibody (ab50002)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TMEFF2 Antibody

Catalogue No.

CSB-PA883439ESR2HU

Reactivity

Human

Immunogen

Recombinant human Tomoregulin-2 protein (41-320AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

41 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:538354( Cow), Entrez Gene:23671( Human), Entrez Gene:56363( Mouse), Omim:605734( Human), SwissProt:Q17QD6( Cow), SwissProt:Q9UIK5( Human), SwissProt:Q9QYM9( Mouse), Unigene:144513( Human), Unigene:245154( Mouse), Unigene:445120( Mouse)

Protein function

May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. .

Protein tissue specificity

Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. .

Protein sequence and domain

Belongs to the tomoregulin family.

Protein post-translational modifications

N-glycosylated. Contains chondroitin sulfate glycosaminoglycans. .; A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or proinflammatory cytokines such as TNFalpha, and is mediated by ADAM17.

Protein cellular localization

Isoform 1: Membrane ; Single-pass type I membrane protein .; Isoform 2: Membrane ; Single-pass type I membrane protein .; Isoform 3: Secreted.

Research area

All research areas>Tumor Suppressor/Apoptosis>TMEFF
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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