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Rabbit Anti-TMEFF2 Antibody (CSB-PA883439ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Tomoregulin-2 Antibody,TR-2 Antibody,Hyperplastic polyposis protein 1 Antibody,Transmembrane protein with EGF-like and two follistatin-like domains Antibody,TMEFF2 Antibody,HPP1 Antibody,TENB2 Antibody,TPEF Antibody,UNQ178/PRO204 AntibodyMore alternative names for the antibody
Cancer/testis antigen family 120 member 2 antibody|CT120.2 antibody|HPP 1 antibody|HPP1 antibody|Hyperplastic polyposis protein 1 antibody|TEFF 2 antibody|TEFF2 antibody|TEFF2_HUMAN antibody|TENB 2 antibody|TENB2 antibody|TMEFF2 antibody|Tomoregulin antibody|Tomoregulin-2 antibody|TPEF antibody|TR 2 antibody|TR antibody|TR-2 antibody|Transmembrane protein containing epidermal growth factor and follistatin domains antibody|Transmembrane protein TENB2 antibody|Transmembrane protein with EGF like and two follistatin like domains 2 antibody|Transmembrane protein with EGF-like and two follistatin-like domains antibody
Anti-TMEFF2 antibody (ab50002)
Anti-TMEFF2 antibody (ab50002)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Tomoregulin-2 protein (41-320AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:538354( Cow), Entrez Gene:23671( Human), Entrez Gene:56363( Mouse), Omim:605734( Human), SwissProt:Q17QD6( Cow), SwissProt:Q9UIK5( Human), SwissProt:Q9QYM9( Mouse), Unigene:144513( Human), Unigene:245154( Mouse), Unigene:445120( Mouse)
|Protein function|| |
May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. .
|Protein tissue specificity|| |
Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. .
|Protein sequence and domain|| |
Belongs to the tomoregulin family.
|Protein post-translational modifications|| |
N-glycosylated. Contains chondroitin sulfate glycosaminoglycans. .; A soluble form (TMEFF2-ECD) is produced by proteolytic shedding. This shedding can be induced by phorbol ester or proinflammatory cytokines such as TNFalpha, and is mediated by ADAM17.
|Protein cellular localization|| |
Isoform 1: Membrane ; Single-pass type I membrane protein .; Isoform 2: Membrane ; Single-pass type I membrane protein .; Isoform 3: Secreted.
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CUSABIO BIOTECH CO.
|Product type|| |
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