Anti-TMEM43 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TMEM43 Antibody (CSB-PA023840ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Transmembrane protein 43 Antibody,Protein LUMA Antibody,TMEM43 Antibody,UNQ2564/PRO6244 Antibody

More alternative names for the antibody
ARVC5 antibody|ARVD5 antibody|EDMD7 antibody|LUMA antibody|Protein LUMA antibody|Tmem43 antibody|TMM43_HUMAN antibody|Transmembrane protein 43 antibody
Anti-TMEM43 antibody [EPR15378(B)] (ab184164)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TMEM43 Antibody

Catalogue No.

CSB-PA023840ESR2HU

Reactivity

Human

Immunogen

Recombinant human Transmembrane protein 43 protein (80-310AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

44 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:79188( Human), Entrez Gene:74122( Mouse), Entrez Gene:362401( Rat), Omim:612048( Human), SwissProt:Q9BTV4 ( Human), SwissProt:Q9DBS1( Mouse), SwissProt:Q5XIP9( Rat), Unigene:517817( Human)

Protein function

May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane (By similarity). .

Protein tissue specificity

Highest expression in placenta. Also found at lower levels in heart, ovary, spleen, small intestine, thymus, prostate and testis. .

Involvement in disease

Arrhythmogenic right ventricular dysplasia, familial, 5 (ARVD5) [MIM:604400]: A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Emery-Dreifuss muscular dystrophy 7, autosomal dominant (EDMD7) [MIM:614302]: A form of Emery-Dreifuss muscular dystrophy, a degenerative myopathy characterized by weakness and atrophy of muscle without involvement of the nervous system, early contractures of the elbows, Achilles tendons and spine, and cardiomyopathy associated with cardiac conduction defects. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the TMEM43 family.

Protein cellular localization

Endoplasmic reticulum . Nucleus inner membrane; Multi-pass membrane protein. Note=Retained in the inner nuclear membrane through interaction with EMD and A- and B-lamins. The N- and C-termini are oriented towards the nucleoplasm. The majority of the hydrophilic domain resides in the endoplasmic reticulum lumen (By similarity). .

Research area

All research areas>Signaling Intermediates>TMEM43
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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