Anti-TNFSF12 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TNFSF12 Antibody (CSB-PA023987ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

APO3 ligand Antibody,TNF-related weak inducer of apoptosis Antibody,TWEAK Antibody,TNFSF12 Antibody,APO3L Antibody, DR3LG Antibody,UNQ181/PRO207 Antibody

More alternative names for the antibody
APO 3 ligand antibody|TNF12_HUMAN antibody|TNFSF 12 antibody|Tnfsf12 antibody|TNFSF12 protein antibody|Tumor necrosis factor (ligand) superfamily member 12 antibody|Tumor necrosis factor ligand superfamily member 12 antibody|Tumor necrosis factor superfamily member 12 antibody|TWEAK antibody|UNQ181/PRO207 antibody
Anti-TWEAK antibody (ab37170)
Close sc-56250|sc-27141|sc-271503|sc-376717|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TNFSF12 Antibody

Catalogue No.

CSB-PA023987ESR1HU

Reactivity

Human

Immunogen

Recombinant human Tumor necrosis factor ligand superfamily member 12 protein (42-123AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

27 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8742( Human), Entrez Gene:21944( Mouse), Entrez Gene:360548( Rat), Omim:602695( Human), SwissProt:O43508( Human), SwissProt:O54907( Mouse), Unigene:54673( Human), Unigene:8983( Mouse)

Protein function

Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion. .

Protein tissue specificity

Highly expressed in adult heart, pancreas, skeletal muscle, brain, colon, small intestine, lung, ovary, prostate, spleen, lymph node, appendix and peripheral blood lymphocytes. Low expression in kidney, testis, liver, placenta, thymus and bone marrow. Also detected in fetal kidney, liver, lung and brain.

Protein sequence and domain

Belongs to the tumor necrosis factor family.

Protein post-translational modifications

The soluble form derives from the membrane form by proteolytic processing.

Protein cellular localization

Cell membrane ; Single-pass type II membrane protein .; Tumor necrosis factor ligand superfamily member 12, secreted form: Secreted.; Isoform TWE-PRIL: Cell membrane; Single-pass membrane protein.

Research area

All research areas>Membrane Receptors>Fn14
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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