Anti-TNFSF13B Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TNFSF13B Antibody (CSB-PA897523ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

B lymphocyte stimulator Antibody,BLyS Antibody,B-cell-activating factor Antibody,BAFF Antibody,Dendritic cell-derived TNF-like molecule Antibody,TNF- and APOL-related leukocyte expressed ligand 1 Antibody,TALL-1 Antibody,CD257 Antibody,TNFSF13B Antibody,BAFF Antibody, BLYS Antibody, TALL1 Antibody, TNFSF20 Antibody, ZTNF4 Antibody

More alternative names for the antibody
TNF homolog that activates apoptosis antibody|TNFSF13B antibody|TNFSF20 antibody|TNLG7A antibody|Tumor necrosis factor (ligand) superfamily member 13b antibody|Tumor necrosis factor ligand 7A antibody|Tumor necrosis factor ligand superfamily member 13b antibody|Tumor necrosis factor ligand superfamily member 20 antibody|Tumor necrosis factor like protein ZTNF4 antibody|Tumor necrosis factor superfamily member 13B antibody|UNQ401 antibody|ZTNF4 antibody
Anti-BAFF antibody [Buffy 2] (ab16081)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TNFSF13B Antibody

Catalogue No.

CSB-PA897523ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Tumor necrosis factor ligand superfamily member 13B protein (76-285AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

31 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:10673( Human), Entrez Gene:24099( Mouse), Omim:603969( Human), SwissProt:Q9Y275( Human), SwissProt:Q9WU72( Mouse), Unigene:525157( Human), Unigene:596110( Human), Unigene:28835( Mouse)

Protein function

Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response. .; Isoform 2 seems to inhibit isoform 1 secretion and bioactivity. .; Isoform 3: Acts as a transcription factor for its own parent gene, in association with NF-kappa-B p50 subunit, at least in autoimmune and proliferative B-cell diseases. The presence of Delta4BAFF is essential for soluble BAFF release by IFNG/IFN-gamma-stimulated monocytes and for B-cell survival. It can directly or indirectly regulate the differential expression of a large number of genes involved in the innate immune response and the regulation of apoptosis. .

Protein tissue specificity

Abundantly expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bone marrow, T-cells and dendritic cells. A lower expression seen in placenta, heart, lung, fetal liver, thymus, and pancreas. Isoform 2 is expressed in many myeloid cell lines. .

Protein sequence and domain

Belongs to the tumor necrosis factor family.

Protein post-translational modifications

The soluble form derives from the membrane form by proteolytic processing.; Isoform 2 is not efficiently shed from the membrane unlike isoform 1. .; N-glycosylated.

Protein cellular localization

Cell membrane; Single-pass type II membrane protein.; Tumor necrosis factor ligand superfamily member 13b, soluble form: Secreted.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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