Anti-TNXB Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TNXB Antibody (CSB-PA024036ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

TN-X Antibody,Hexabrachion-like protein Antibody,TNXB Antibody,HXBL Antibody,TNX Antibody,TNXB1 Antibody,TNXB2 Antibody, XB Antibody

More alternative names for the antibody
EDS3 antibody|Ehlers Danlos like syndrome antibody|Growth inhibiting protein 45 antibody|Hexabrachion like protein antibody|Hexabrachion-like protein antibody|HXBL antibody|NXB2 antibody|Tenascin X precursor antibody|Tenascin XB antibody|Tenascin XB1 antibody|Tenascin XB2 antibody|Tenascin-X antibody|TENX antibody|TENX_HUMAN antibody|TN X antibody|TN-X antibody|TNX antibody|TNXB antibody|TNXB1 antibody|TNXB2 antibody|TNXBS antibody|VUR8 antibody|XB antibody|XBS antibody
Anti-TNXB antibody (ab198871)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TNXB Antibody

Catalogue No.

CSB-PA024036ESR2HU

Reactivity

Human

Immunogen

Recombinant human Tenascin-X protein (3933-4242AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

458 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:7148( Human), Omim:600985( Human), SwissProt:P22105( Human), Unigene:485104( Human)

Protein function

Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors. .

Protein tissue specificity

Highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. Isoform XB-short is only expressed in the adrenal gland.

Involvement in disease

Ehlers-Danlos syndrome due to tenascin X deficiency (EDSTNXD) [MIM:606408]: An Ehlers-Danlos-like syndrome characterized by hyperextensible skin, hypermobile joints, and tissue fragility. Tenascin-X-deficient patients, however, lack atrophic scars, a major diagnostic criteria for classic Ehlers-Danlos. Delayed wound healing, which is also common in classic EDS, is only present in a subset of patients. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Vesicoureteral reflux 8 (VUR8) [MIM:615963]: A disease belonging to the group of congenital anomalies of the kidney and urinary tract. It is characterized by the reflux of urine from the bladder into the ureters and sometimes into the kidneys, and is a risk factor for urinary tract infections. Primary disease results from a developmental defect of the ureterovesical junction. In combination with intrarenal reflux, the resulting inflammatory reaction may result in renal injury or scarring, also called reflux nephropathy. Extensive renal scarring impairs renal function and may predispose patients to hypertension, proteinuria, renal insufficiency and end-stage renal disease. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the tenascin family.

Protein cellular localization

Secreted, extracellular space, extracellular matrix.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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