Anti-TRADD Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TRADD Antibody (CSB-PA621879ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

TNFR1-associated DEATH domain protein Antibody,TNFRSF1A-associated via death domain Antibody,TRADD Antibody

More alternative names for the antibody
9130005N23Rik antibody|AA930854 antibody|TNFR1 associated DEATH domain protein antibody|TNFR1-associated DEATH domain protein antibody|TNFRSF1A associated via death domain antibody|TNFRSF1A-associated via death domain antibody|tradd antibody|TRADD_HUMAN antibody|Tumor necrosis factor receptor type 1 associated DEATH domain protein antibody|Tumor necrosis factor receptor type 1-associated DEATH domain protein antibody
Anti-TRADD antibody [EPR3604] (ab110644)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TRADD Antibody

Catalogue No.

CSB-PA621879ESR2HU

Reactivity

Human

Immunogen

Recombinant human Tumor necrosis factor receptor type 1-associated DEATH domain protein (1-312AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

34 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8717( Human), Entrez Gene:71609( Mouse), Entrez Gene:246756( Rat), Omim:603500( Human), SwissProt:Q15628( Human), SwissProt:Q3U0V2( Mouse), Unigene:460996( Human), Unigene:264255( Mouse)

Protein function

The nuclear form acts as a tumor suppressor by preventing ubiquitination and degradation of isoform p19ARF/ARF of CDKN2A by TRIP12: acts by interacting with TRIP12, leading to disrupt interaction between TRIP12 and isoform p19ARF/ARF of CDKN2A (By similarity). Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD. Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B. .

Protein tissue specificity

Found in all examined tissues.

Protein sequence and domain

Requires the intact death domain to associate with TNFRSF1A/TNFR1.

Protein cellular localization

Nucleus . Cytoplasm . Cytoplasm, cytoskeleton . Note=Shuttles between the cytoplasm and the nucleus. .

Research area

All research areas>Tumor Suppressor/Apoptosis>TRADD
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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