Anti-TRPM7 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TRPM7 Antibody (CSB-PA857013ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Transient receptor potential cation channel subfamily M member 7 Antibody,Channel-kinase 1 Antibody,Long transient receptor potential channel 7 Antibody,LTrpC-7 Antibody,LTrpC7 Antibody,TRPM7 Antibody,CHAK1 Antibody,LTRPC7 Antibody

More alternative names for the antibody
ALSPDC antibody|CHAK antibody|CHAK1 antibody|Channel kinase 1 antibody|Channel-kinase 1 antibody|Long transient receptor potential channel 7 antibody|LTrpC-7 antibody|LTrpC7 antibody|Transient receptor potential cation channel subfamily M member 7 antibody|TRP PLIK antibody|TRPM7 antibody|TRPM7_HUMAN antibody
Anti-TRPM7 antibody [S74-25] (ab85016)
Close sc-271099|sc-31381|sc-19562|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-TRPM7 Antibody

Catalogue No.

CSB-PA857013ESR2HU

Reactivity

Human

Immunogen

Recombinant human Transient receptor potential cation channel subfamily M member 7 protein (756-855AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

212 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:54822( Human), Entrez Gene:58800( Mouse), Entrez Gene:679906( Rat), Omim:605692( Human), SwissProt:Q96QT4( Human), SwissProt:Q923J1( Mouse), SwissProt:Q925B3( Rat), Unigene:512894( Human), Unigene:244705( Mouse), Unigene:86991( Rat)

Protein function

Essential ion channel and serine/threonine-protein kinase. Divalent cation channel permeable to calcium and magnesium. Has a central role in magnesium ion homeostasis and in the regulation of anoxic neuronal cell death. Involved in TNF-induced necroptosis downstream of MLKL by mediating calcium influx. The kinase activity is essential for the channel function. May be involved in a fundamental process that adjusts plasma membrane divalent cation fluxes according to the metabolic state of the cell. Phosphorylates annexin A1 (ANXA1). .

Involvement in disease

Amyotrophic lateral sclerosis-parkinsonism/dementia complex 1 (ALS-PDC1) [MIM:105500]: A neurodegenerative disorder characterized by chronic, progressive and uniformly fatal amyotrophic lateral sclerosis and parkinsonism-dementia. Both diseases are known to occur in the same kindred, the same sibship and even the same individual. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein sequence and domain

In the C-terminal section; belongs to the protein kinase superfamily. Alpha-type protein kinase family. ALPK subfamily.; In the N-terminal section; belongs to the transient receptor (TC 1.A.4) family. LTrpC subfamily. TRPM7 sub-subfamily.

Protein post-translational modifications

Autophosphorylated. .

Protein cellular localization

Membrane ; Multi-pass membrane protein .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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