Anti-TTLL7 Antibody

$99.00$319.00

Reactivity: Human,Rat
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-TTLL7 Antibody (CSB-PA765082ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Tubulin polyglutamylase TTLL7Curated Antibody,Testis development protein NYD-SP30 Antibody,TTLL7 Antibody

More alternative names for the antibody
RP5-836J3.2 antibody|Testis development protein NYD-SP30 antibody|Ttll7 antibody|TTLL7_HUMAN antibody|Tubulin polyglutamylase TTLL7 antibody|Tubulin tyrosine ligase like family member 7 antibody|Tubulin–tyrosine ligase-like protein 7 antibody
Anti-TTLL7 antibody – N-terminal (ab155547)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-TTLL7 Antibody

Catalogue No.

CSB-PA765082ESR2HU

Reactivity

Human, Rat

Immunogen

Recombinant human Tubulin polyglutamylase TTLL7 protein (1-260AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

102 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:522221( Cow), Entrez Gene:79739( Human), Entrez Gene:70892( Mouse), SwissProt:Q6ZT98( Human), SwissProt:A4Q9F0( Mouse), Unigene:445826( Human)

Protein function

Polyglutamylase which preferentially modifies beta-tubulin (PubMed:25959773). Mediates both ATP-dependent initiation and elongation of polyglutamylation of microtubules (PubMed:25959773). Required for neurite growth; responsible for the strong increase in tubulin polyglutamylation during postnatal neuronal maturation (By similarity). .

Protein tissue specificity

Highly expressed in the nervous system including spinal cord, thalamus, hippocampus, hypothalamus and cerebellum. .

Protein sequence and domain

Belongs to the tubulin–tyrosine ligase family. The enzyme uses its core to engage the disordered anionic tails of alpha- and beta-tubulin and the flexible c-MTBD (cationic microtubule binding domain) region to bind the microtubule and position itself for beta-tail modification. The c-MTBD region is positively charged and becomes ordered when bound to microtubules: it interacts with a negatively charged patch on alpha-tubulin. The presence of positive charges in the c-MTBD region is essential for proper binding.

Protein cellular localization

Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cell projection, dendrite . Perikaryon . Note=In cells with primary cilia, found in both cilia and basal bodies. In neuronal cells, found in dendrites and perikaryon. .

Research area

All research areas>Structural Proteins>TTLL
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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