Anti-U2AF1L4 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-U2AF1L4 Antibody (CSB-PA837850ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Splicing factor U2AF 26 kDa subunit Antibody,U2 auxiliary factor 26 Antibody,U2 small nuclear RNA auxiliary factor 1-like protein 4 Antibody,U2AF1-like 4 Antibody,U2AF1L4 Antibody,U2AF1-RS3 Antibody,U2AF1L3 Antibody

More alternative names for the antibody
FLJ35525 antibody|MGC33901 antibody|Splicing factor U2AF 26 kDa subunit antibody|U2 auxiliary factor 26 antibody|U2 small nuclear RNA auxiliary factor 1 like 3 antibody|U2 small nuclear RNA auxiliary factor 1 like 4 antibody|U2 small nuclear RNA auxiliary factor 1 like protein 3 antibody|U2 small nuclear RNA auxiliary factor 1 like protein 4 antibody|U2 small nuclear RNA auxiliary factor 1-like protein 3 antibody|U2 small nuclear RNA auxiliary factor 1-like protein 4 antibody|U2(RNU2) small nuclear RNA auxiliary factor 1 like 3 antibody|U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3 antibody|U2AF1 like protein 3 antibody|U2AF1 RS3 antibody|U2AF1-like protein 3 antibody|U2AF1L3V1 antibody|U2AF1L4 antibody|U2AF1RS3 antibody|U2af26 antibody|U2AF4_HUMAN antibody|U2RNU2 small nuclear RNA auxiliary factor 1 like 3 antibody|U2RNU2 small nuclear RNA auxiliary factor 1 like protein 3 antibody
Anti-U2AF1L3 antibody [EPR14349] (ab188582)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-U2AF1L4 Antibody

Catalogue No.

CSB-PA837850ESR1HU

Reactivity

Human

Immunogen

Recombinant human Splicing factor U2AF 26 kDa subunit protein (1-202AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

25 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:199746( Human), Entrez Gene:233073( Mouse), Entrez Gene:361542( Rat), Omim:601080( Human), SwissProt:Q8WU68( Human), SwissProt:Q8BGJ9( Mouse), SwissProt:Q7TP17( Rat), Unigene:351558( Human), Unigene:34790( Mouse), Unigene:145185( Rat)

Protein function

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3′-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3′-splice site (By similarity). Shows a preference for AGC or AGA (By similarity). .

Protein tissue specificity

Isoform 2 is widely expressed. Isoform 3 is highly expressed in heart, brain and lung, lower expressed in thymus and much lower expressed in peripheral blood leukocytes. .

Protein sequence and domain

Belongs to the splicing factor SR family. The second zinc finger in necessary for interaction with GFI1 and for alternative pre-mRNA splicing events.; The region 162-220 is essential for the nuclear import of the protein in spite of the absence of a nuclear localization signal (NLS). This region is essential for the interaction with C1QBP, interaction which is required for the nuclear translocation. This region may be involved in the localization in nuclear dot-like structures and it also confers the ability of nucleo-cytoplasmic shuttling.

Protein cellular localization

Nucleus . Nucleus speckle . Cytoplasm . Note=Interaction with C1QBP is required for the nuclear translocation. Displays active nucleo-cytoplasmic shuttling. .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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