Anti-UBE2S Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-UBE2S Antibody (CSB-PA623095DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Ubiquitin-conjugating enzyme E2 S Antibody,E2 ubiquitin-conjugating enzyme S Antibody,E2-EPF Antibody,Ubiquitin carrier protein S Antibody,Ubiquitin-conjugating enzyme E2-24 kDa Antibody,Ubiquitin-conjugating enzyme E2-EPF5 Antibody,Ubiquitin-protein ligase S Antibody,UBE2S Antibody,E2EPF Antibody,OK/SW-cl.73 Antibody

More alternative names for the antibody
AA409170 antibody|E2 EPF antibody|E2-EPF antibody|E2EPF antibody|EPF5 antibody|MGC101982 antibody|Ube2s antibody|UBE2S_HUMAN antibody|Ubiquitin carrier protein S antibody|Ubiquitin conjugating enzyme E2 24 kD antibody|Ubiquitin conjugating enzyme E2 24 kDa antibody|Ubiquitin conjugating enzyme E2 EPF5 antibody|Ubiquitin conjugating enzyme E2 S antibody|Ubiquitin conjugating enzyme E2S antibody|Ubiquitin protein ligase S antibody|Ubiquitin-conjugating enzyme E2 S antibody|Ubiquitin-conjugating enzyme E2-24 kDa antibody|Ubiquitin-conjugating enzyme E2-EPF5 antibody|Ubiquitin-protein ligase S antibody
Anti-UBE2S antibody (ab177508)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-UBE2S Antibody

Catalogue No.

CSB-PA623095DSR1HU

Reactivity

Human

Immunogen

Recombinant human Ubiquitin-conjugating enzyme E2 S protein (1-222AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

23 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:456304( Chimpanzee), Entrez Gene:617703( Cow), Entrez Gene:27338( Human), Entrez Gene:77891( Mouse), Entrez Gene:700592( Rhesus monkey), Entrez Gene:379075( Xenopus laevis), Entrez Gene:565498( Zebrafish), Omim:610309( Human), SwissProt:Q1RML1( Cow), SwissProt:Q16763( Human), SwissProt:Q921J4( Mouse), SwissProt:A1L3K1( Xenopus laevis), SwissProt:Q76EZ2( Xenopus laevis), SwissProt:Q8AVU2( Xenopus laevis), SwissProt:Q4V908( Zebrafish), Unigene:396393( Human), Unigene:389787( Mouse), Unigene:132389( Zebrafish)

Protein function

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. Catalyzes ‘Lys-11’-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by specifically elongating ‘Lys-11’-linked polyubiquitin chains initiated by the E2 enzyme UBE2C/UBCH10 on APC/C substrates, enhancing the degradation of APC/C substrates by the proteasome and promoting mitotic exit. Also acts by elongating ubiquitin chains initiated by the E2 enzyme UBE2D1/UBCH5 in vitro; it is however unclear whether UBE2D1/UBCH5 acts as an E2 enzyme for the APC/C in vivo. Also involved in ubiquitination and subsequent degradation of VHL, resulting in an accumulation of HIF1A. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, except ‘Lys-48’-linked polyubiquitination. .

Protein sequence and domain

Belongs to the ubiquitin-conjugating enzyme family.

Protein post-translational modifications

Autoubiquitinated by the APC/C complex during G1, leading to its degradation by the proteasome. .

Research area

All research areas>Synthesis and Degradation>UBE
(View all antibody categories related to Synthesis and Degradation)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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