Anti-UCHL3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-UCHL3 Antibody (CSB-PA025543DSR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

UCH-L3 Antibody,Ubiquitin thioesterase L3 Antibody,UCHL3 Antibody

More alternative names for the antibody
Ubiquitin C terminal esterase L1 antibody|Ubiquitin carboxyl terminal esterase L1 antibody|Ubiquitin carboxyl terminal esterase L3 antibody|Ubiquitin carboxyl terminal hydrolase isozyme L1 antibody|Ubiquitin carboxyl terminal hydrolase isozyme L3 antibody|Ubiquitin thiolesterase antibody|UCHL1 antibody|UCHL3 antibody
Anti-UCHL1+3 antibody (ab75275)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-UCHL3 Antibody

Catalogue No.

CSB-PA025543DSR2HU

Reactivity

Human

Immunogen

Recombinant human Ubiquitin carboxyl-terminal hydrolase isozyme L3 protein (1-220AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

26 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:7345( Human), Entrez Gene:7347( Human), Entrez Gene:22223( Mouse), Entrez Gene:50933( Mouse), Entrez Gene:29545( Rat), Entrez Gene:498560( Rat), Omim:191342( Human), Omim:603090( Human), SwissProt:P09936( Human), SwissProt:P15374( Human), SwissProt:Q9JKB1( Mouse), SwissProt:Q9R0P9( Mouse), SwissProt:Q00981( Rat), SwissProt:Q91Y78( Rat)

Protein function

Deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. Thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. Has a 10-fold preference for Arg and Lys at position P3″, and exhibits a preference towards ‘Lys-48’-linked Ubiquitin chains. Deubiquitinates ENAC in apical compartments, thereby regulating apical membrane recycling. Indirectly increases the phosphorylation of IGFIR, AKT and FOXO1 and promotes insulin-signaling and insulin-induced adipogenesis. Required for stress-response retinal, skeletal muscle and germ cell maintenance. May be involved in working memory. Can hydrolyze UBB(+1), a mutated form of ubiquitin which is not effectively degraded by the proteasome and is associated with neurogenerative disorders. .

Protein tissue specificity

Highly expressed in heart, skeletal muscle, and testis. .

Protein sequence and domain

Belongs to the peptidase C12 family.

Protein cellular localization

Cytoplasm.

Research area

All research areas>Neurobiology Antibodies>UCH-L
(View all antibody categories related to Neurobiology Antibodies)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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