Anti-UCP1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-UCP1 Antibody (CSB-PA025554ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

UCP 1 Antibody,Solute carrier family 25 member 7 Antibody,Thermogenin Antibody,UCP1 Antibody,SLC25A7 Antibody,UCP Antibody

More alternative names for the antibody

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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-UCP1 Antibody

Catalogue No.

CSB-PA025554ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Mitochondrial brown fat uncoupling protein 1 protein (1-307AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

33 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Protein function

Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates to non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance (By similarity). Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane (PubMed:24196960). However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria (By similarity). .

Protein tissue specificity

Brown adipose tissue. .

Protein sequence and domain

Belongs to the mitochondrial carrier (TC 2.A.29) family.

Protein post-translational modifications

May undergo sulfenylation upon cold exposure. May increase the sensitivity of UCP1 thermogenic function to the activation by noradrenaline probably through structural effects. .; May undergo ubiquitin-mediated proteasomal degradation. .

Protein cellular localization

Mitochondrion inner membrane ; Multi-pass membrane protein .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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