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Rabbit Anti-ULBP2 Antibody (CSB-PA880151ESR1HU)
Supplier: CUSABIO BIOTECH CO.
N2DL-2;NKG2DL2;ALCAN-alpha;Retinoic acid early transcript 1H;UL16-binding protein 2;ULBP2;N2DL2 Antibody,RAET1H AntibodyMore alternative names for the antibody
ALCAN alpha antibody|ALCAN-alpha antibody|N2DL 2 antibody|N2DL-2 antibody|N2DL2 antibody|N2DL2_HUMAN antibody|NKG2D ligand 2 antibody|NKG2D ligand 2 precursor antibody|NKG2DL2 antibody|RAET1H antibody|Retinoic acid early transcript 1 H antibody|Retinoic acid early transcript 1H antibody|UL16 binding protein 2 antibody|UL16-binding protein 2 antibody|ULBP2 antibody
Anti-ULBP2 antibody (ab88645)
Anti-ULBP2 antibody (ab88645)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human NKG2D ligand 2 protein (26-216AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=80328" target="_blank">Entrez Gene:80328( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/605698" target="_blank">Omim:605698( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q9BZM5" target="_blank">SwissProt:Q9BZM5( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=656778" target="_blank">Unigene:656778( Human)</a>
|Protein function|| |
Ligand for the KLRK1/NKG2D receptor, together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to KLRK1/NKG2D induces calcium mobilization and activation of the JAK2, STAT5, ERK and PI3K kinase/Akt signal transduction pathway. In CMV infected cells, interacts with soluble CMV glycoprotein UL16. The interaction with UL16 blocked the interaction with the KLRK1/NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. UL16 also causes ULBP2 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. .
|Protein tissue specificity|| |
Expressed in various types of cancer cell lines and in the fetus, but not in normal tissues. .
|Protein sequence and domain|| |
Belongs to the MHC class I family.
|Protein cellular localization|| |
Cell membrane; Lipid-anchor, GPI-anchor. Secreted.
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Lymphocyte-Signaling/">Lymphocyte Signaling</a>><a href="https://antibodyplus.com/product-tag/ULBPRAET1/">ULBP/RAET1</a><br><a href="https://antibodyplus.com/product-tag/Lymphocyte-Signaling/"> (View all antibody categories related to Lymphocyte Signaling)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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