Anti-VANGL2 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-VANGL2 Antibody (CSB-PA890750ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Vang-like protein 2 Antibody,Loop-tail protein 1 homolog Antibody,Strabismus 1 Antibody,Van Gogh-like protein 2 Antibody,VANGL2 Antibody,KIAA1215 Antibody,STB1 Antibody

More alternative names for the antibody
Homolog of Drosophila strabismus antibody|KIAA1215 antibody|Loop tail associated protein antibody|loop tail protein 1 homolog antibody|Loop-tail protein 1 homolog antibody|LPP 1 antibody|LPP1 antibody|LTAP antibody|MGC119403 antibody|MGC119404 antibody|STB 1 antibody|STB1 antibody|STBM 1 antibody|STBM antibody|STBM1 antibody|Strabismus 1 antibody|van Gogh like protein 2 antibody|Van Gogh-like protein 2 antibody|Vang (van gogh, Drosophila) like 2 antibody|Vang like 2 (van gogh, Drosophila) antibody|vang like 2 antibody|vang like protein 2 antibody|Vang-like protein 2 antibody|VANG2_HUMAN antibody|VANGL 2 antibody|VANGL planar cell polarity protein 2 antibody|Vangl2 antibody
Anti-VANGL2 antibody (ab60172)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-VANGL2 Antibody

Catalogue No.

CSB-PA890750ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Vang-like protein 2 protein (1-110AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

59 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:57216( Human), Entrez Gene:93840( Mouse), Entrez Gene:289229( Rat), Entrez Gene:245949( Zebrafish), Omim:600533 ( Human), SwissProt:Q9ULK5( Human), SwissProt:Q91ZD4( Mouse), SwissProt:P84889( Rat), SwissProt:Q8UVJ6( Zebrafish), Unigene:99477( Human), Unigene:36148( Mouse), Unigene:392110( Mouse), Unigene:198958( Rat), Unigene:91583( Zebrafish)

Protein function

Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). .

Involvement in disease

Neural tube defects (NTD) [MIM:182940]: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy. Failure of neural tube closure can occur at any level of the embryonic axis. Common NTD forms include anencephaly, myelomeningocele and spina bifida, which result from the failure of fusion in the cranial and spinal region of the neural tube. NTDs have a multifactorial etiology encompassing both genetic and environmental components. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the Vang family.

Protein cellular localization

Cell membrane ; Multi-pass membrane protein .

Research area

All research areas>Neurobiology Antibodies>Vangl
(View all antibody categories related to Neurobiology Antibodies)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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