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Rabbit Anti-VANGL2 Antibody (CSB-PA890750ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Vang-like protein 2 Antibody,Loop-tail protein 1 homolog Antibody,Strabismus 1 Antibody,Van Gogh-like protein 2 Antibody,VANGL2 Antibody,KIAA1215 Antibody,STB1 AntibodyMore alternative names for the antibody
Homolog of Drosophila strabismus antibody|KIAA1215 antibody|Loop tail associated protein antibody|loop tail protein 1 homolog antibody|Loop-tail protein 1 homolog antibody|LPP 1 antibody|LPP1 antibody|LTAP antibody|MGC119403 antibody|MGC119404 antibody|STB 1 antibody|STB1 antibody|STBM 1 antibody|STBM antibody|STBM1 antibody|Strabismus 1 antibody|van Gogh like protein 2 antibody|Van Gogh-like protein 2 antibody|Vang (van gogh, Drosophila) like 2 antibody|Vang like 2 (van gogh, Drosophila) antibody|vang like 2 antibody|vang like protein 2 antibody|Vang-like protein 2 antibody|VANG2_HUMAN antibody|VANGL 2 antibody|VANGL planar cell polarity protein 2 antibody|Vangl2 antibody
Anti-VANGL2 antibody (ab60172)
Anti-VANGL2 antibody (ab60172)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-1:5000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Vang-like protein 2 protein (1-110AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:57216( Human), Entrez Gene:93840( Mouse), Entrez Gene:289229( Rat), Entrez Gene:245949( Zebrafish), Omim:600533 ( Human), SwissProt:Q9ULK5( Human), SwissProt:Q91ZD4( Mouse), SwissProt:P84889( Rat), SwissProt:Q8UVJ6( Zebrafish), Unigene:99477( Human), Unigene:36148( Mouse), Unigene:392110( Mouse), Unigene:198958( Rat), Unigene:91583( Zebrafish)
|Protein function|| |
Involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. Plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. Required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. Required for cell surface localization of FZD3 and FZD6 in the inner ear (By similarity). .
|Involvement in disease|| |
Neural tube defects (NTD) [MIM:182940]: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy. Failure of neural tube closure can occur at any level of the embryonic axis. Common NTD forms include anencephaly, myelomeningocele and spina bifida, which result from the failure of fusion in the cranial and spinal region of the neural tube. NTDs have a multifactorial etiology encompassing both genetic and environmental components. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the Vang family.
|Protein cellular localization|| |
Cell membrane ; Multi-pass membrane protein .
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CUSABIO BIOTECH CO.
|Product type|| |
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