Anti-VSX1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-VSX1 Antibody (CSB-PA025938ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Visual system homeobox 1 Antibody,Homeodomain protein RINX Antibody,Retinal inner nuclear layer homeobox protein Antibody,Transcription factor VSX1 Antibody,VSX1 Antibody,RINX Antibody

More alternative names for the antibody
CAASDS antibody|Homeodomain protein RINX antibody|KTCN antibody|KTCN1 antibody|Posterior polymorphous corneal dystrophy antibody|PPCD antibody|PPD antibody|Retinal inner nuclear layer homeobox protein antibody|RINX antibody|Transcription factor VSX1 antibody|Visual system homeobox 1 antibody|Visual system homeobox 1 homolog, CHX10 like antibody|Visual system homeobox 1 homolog, CHX10 like (zebrafish) antibody|VSX1 antibody|VSX1_HUMAN antibody
Anti-VSX1 antibody (ab105818)
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Recommended applications: ELISA, WB

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-VSX1 Antibody

Catalogue No.

CSB-PA025938ESR1HU

Reactivity

Human

Immunogen

Recombinant human Visual system homeobox 1 protein (1-170AA)

Host

Rabbit

Applications

ELISA, WB

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

38 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:30813( Human), Entrez Gene:114889( Mouse), Entrez Gene:689704( Rat), Omim:605020( Human), SwissProt:Q9NZR4( Human), SwissProt:Q91V10( Mouse), Unigene:274264( Human), Unigene:207061( Mouse)

Protein function

Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development.

Protein tissue specificity

In the adult eye, expressed in lens, iris, ciliary body, choroid, optical nerve head and, most strongly, in retina, but not expressed in sclera and cornea. According to PubMed 11978762, expressed in adult retina but not in lens and cornea. Within adult retina, found exclusively in the inner nuclear layer. Isoform 1, isoform 2, isoform 3 and isoform 4 expressed in adult retina, but not in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. Not expressed in thymus and spleen. Expressed in embryonic craniofacial tissue. Expressed in fetal (week 14) retina. Strongly expressed in neonatal retina (day 0), weakly in neonatal lens (day 0), choroid (day 0) and cornea (day 0, 4; month 9). .

Involvement in disease

Keratoconus 1 (KTCN1) [MIM:148300]: Frequent corneal dystrophy with an incidence that varies from 50 to 230 per 100’000. The cornea assumes a conical shape as a result of a progressive non-inflammatory thinning of the corneal stroma. Keratoconus is most often an isolated sporadic condition with cases of autosomal dominant and autosomal recessive transmission. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Craniofacial anomalies and anterior segment dysgenesis syndrome (CAASDS) [MIM:614195]: A disorder with extremely variable expressivity. Clinical features include wide interpupillary distance, abnormal corneal endothelium, unusual pinnae, partially to completely empty sella turcica, posterior fossa cyst, anterior encephalocele, and/or hydrocephalus. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the paired homeobox family.

Protein cellular localization

Nucleus .

Research area

All research areas>Homeodomain Proteins>VSX
(View all antibody categories related to Homeodomain Proteins)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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