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Rabbit Anti-VSX1 Antibody (CSB-PA025938ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Visual system homeobox 1 Antibody,Homeodomain protein RINX Antibody,Retinal inner nuclear layer homeobox protein Antibody,Transcription factor VSX1 Antibody,VSX1 Antibody,RINX AntibodyMore alternative names for the antibody
CAASDS antibody|Homeodomain protein RINX antibody|KTCN antibody|KTCN1 antibody|Posterior polymorphous corneal dystrophy antibody|PPCD antibody|PPD antibody|Retinal inner nuclear layer homeobox protein antibody|RINX antibody|Transcription factor VSX1 antibody|Visual system homeobox 1 antibody|Visual system homeobox 1 homolog, CHX10 like antibody|Visual system homeobox 1 homolog, CHX10 like (zebrafish) antibody|VSX1 antibody|VSX1_HUMAN antibody
Anti-VSX1 antibody (ab105818)
Anti-VSX1 antibody (ab105818)
Recommended applications: ELISA, WB
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Visual system homeobox 1 protein (1-170AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:30813( Human), Entrez Gene:114889( Mouse), Entrez Gene:689704( Rat), Omim:605020( Human), SwissProt:Q9NZR4( Human), SwissProt:Q91V10( Mouse), Unigene:274264( Human), Unigene:207061( Mouse)
|Protein function|| |
Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster. May regulate the activity of the LCR and the cone opsin genes at earlier stages of development.
|Protein tissue specificity|| |
In the adult eye, expressed in lens, iris, ciliary body, choroid, optical nerve head and, most strongly, in retina, but not expressed in sclera and cornea. According to PubMed 11978762, expressed in adult retina but not in lens and cornea. Within adult retina, found exclusively in the inner nuclear layer. Isoform 1, isoform 2, isoform 3 and isoform 4 expressed in adult retina, but not in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. Not expressed in thymus and spleen. Expressed in embryonic craniofacial tissue. Expressed in fetal (week 14) retina. Strongly expressed in neonatal retina (day 0), weakly in neonatal lens (day 0), choroid (day 0) and cornea (day 0, 4; month 9). .
|Involvement in disease|| |
Keratoconus 1 (KTCN1) [MIM:148300]: Frequent corneal dystrophy with an incidence that varies from 50 to 230 per 100’000. The cornea assumes a conical shape as a result of a progressive non-inflammatory thinning of the corneal stroma. Keratoconus is most often an isolated sporadic condition with cases of autosomal dominant and autosomal recessive transmission. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Craniofacial anomalies and anterior segment dysgenesis syndrome (CAASDS) [MIM:614195]: A disorder with extremely variable expressivity. Clinical features include wide interpupillary distance, abnormal corneal endothelium, unusual pinnae, partially to completely empty sella turcica, posterior fossa cyst, anterior encephalocele, and/or hydrocephalus. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the paired homeobox family.
|Protein cellular localization|| |
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|Product type|| |
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