Anti-WDR45 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-WDR45 Antibody (CSB-PA852773ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

WD repeat domain phosphoinositide-interacting protein 4 Antibody,WIPI-4 Antibody,WD repeat-containing protein 45 Antibody,WDR45 Antibody,WDRX1 Antibody,WDRXI4 Antibody,WIPI4 Antibody,JM5 Antibody

More alternative names for the antibody
JM5 antibody|NBIA4 antibody|WD repeat containing protein 45 antibody|WD repeat domain 45 antibody|WD repeat domain phosphoinositide interacting protein 4 antibody|WD repeat domain, X linked 1 antibody|WD45 repeat protein interacting with phosphoinositides 4 antibody|WDRX1 antibody|WDRXI4 antibody|WIPI 4 antibody|WIPI-4 antibody|WIPI4 antibody
Anti-WDR45 antibody (ab168532)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-WDR45 Antibody

Catalogue No.

CSB-PA852773ESR1HU

Reactivity

Human

Immunogen

Recombinant human WD repeat domain phosphoinositide-interacting protein 4 protein (1-360AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

39 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:11152( Human), Entrez Gene:54636( Mouse), Entrez Gene:446846( Xenopus laevis), Entrez Gene:393200( Zebrafish), Omim:300526( Human), SwissProt:Q9Y484( Human), SwissProt:Q91VM3( Mouse), SwissProt:Q6DCV0( Xenopus laevis), SwissProt:Q7ZUX3( Zebrafish), Unigene:632807( Human), Unigene:305725( Mouse), Unigene:7559( Xenopus laevis), Unigene:79570( Zebrafish)

Protein function

Plays an important role in the autophagy pathway, which is the major intracellular degradation system by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. .

Protein tissue specificity

Ubiquitously expressed, with high expression in skeletal muscle and heart. Weakly expressed in liver and placenta. Expression is down-regulated in pancreatic and in kidney tumors. .

Involvement in disease

Neurodegeneration with brain iron accumulation 5 (NBIA5) [MIM:300894]: A neurodegenerative disorder associated with iron accumulation in the brain, primarily in the basal ganglia. NBIA5 is characterized by global developmental delay in early childhood that is essentially static, with slow motor and cognitive gains until adolescence or early adulthood. In young adulthood, affected individuals develop progressive dystonia, parkinsonism, extrapyramidal signs, and dementia resulting in severe disability. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the WD repeat SVP1 family.

Research area

All research areas>Signaling Intermediates>WIPI
(View all antibody categories related to Signaling Intermediates)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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