Anti-WDR77 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-WDR77 Antibody (CSB-PA859030ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

MEP-50 Antibody,Androgen receptor cofactor p44 Antibody,WD repeat-containing protein 77 Antibody,p44/Mep50 Antibody,WDR77 Antibody,MEP50 Antibody, WD45 Antibody,HKMT1069 Antibody, Nbla10071 Antibody

More alternative names for the antibody
2610312E17Rik antibody|Androgen receptor cofactor p44 antibody|C79984 antibody|HKMT1069 antibody|MEP 50 antibody|MEP-50 antibody|MEP50 antibody|MEP50_HUMAN antibody|Methylosome protein 50 antibody|MGC2722 antibody|Nbla10071 antibody|p44 antibody|p44/Mep50 antibody|RGD1310479 antibody|RP11 552M11.3 antibody|WD repeat containing protein 77 antibody|WD repeat domain 77 antibody|WD repeat-containing protein 77 antibody|WDR77 antibody
Anti-WDR77 antibody [EPR10708(B)] (ab154190)
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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-WDR77 Antibody

Catalogue No.

CSB-PA859030ESR2HU

Reactivity

Human

Immunogen

Recombinant human Methylosome protein 50 protein (1-260AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

36 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:79084( Human), Entrez Gene:70465( Mouse), Entrez Gene:310769( Rat), Omim:611734( Human), SwissProt:Q9BQA1( Human), SwissProt:Q99J09( Mouse), SwissProt:Q4QR85( Rat), Unigene:204773( Human), Unigene:5110( Mouse), Unigene:14128( Rat)

Protein function

Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage. .

Protein tissue specificity

Highly expressed in heart, skeletal muscle, spleen, testis, uterus, prostate and thymus. In testis, expressed in germ cells and Leydig cells, but not in peritubular myocytes, nor in Sertoli cells. Expressed in prostate cancers, in seminomas and in Leydig cell tumors. .

Protein cellular localization

Nucleus. Cytoplasm. Note=Nuclear in Leydig cells and cytoplasmic in germ cells during fetal testicular development. In adult testis, predominantly nuclear. Subcellular location varies from nuclear to cytoplasmic in various tumors.

Research area

All research areas>Signaling Intermediates>WDR
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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