Anti-ZEB2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ZEB2 Antibody (CSB-PA026425DSR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Smad-interacting protein 1 Antibody,SMADIP1 Antibody,Zinc finger homeobox protein 1b Antibody,ZEB2 Antibody

More alternative names for the antibody
FLJ42816 antibody|HSPC082 antibody|KIAA0569 antibody|SIP 1 antibody|SIP1 antibody|Smad-interacting protein 1 antibody|SMADIP 1 antibody|SMADIP1 antibody|ZEB 2 antibody|Zeb2 antibody|ZEB2_HUMAN antibody|Zfhx1b antibody|ZFHX1B protein antibody|Zfx1b antibody|Zinc finger E box binding protein 2 antibody|Zinc finger E-box-binding homeobox 2 antibody|Zinc finger homeobox 1b antibody|zinc finger homeobox protein 1 antibody|Zinc finger homeobox protein 1b antibody
Anti-Smad Interacting Protein 1 antibody (ab138222)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ZEB2 Antibody

Catalogue No.

CSB-PA026425DSR2HU

Reactivity

Human

Immunogen

Recombinant human Zinc finger E-box-binding homeobox 2 protein (1050-1214AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

136 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9839( Human), Entrez Gene:24136( Mouse), Entrez Gene:311071( Rat), Omim:605802( Human), SwissProt:O60315( Human), SwissProt:Q9R0G7( Mouse), Unigene:34871( Human), Unigene:440702( Mouse), Unigene:59710( Rat)

Protein function

Transcriptional inhibitor that binds to DNA sequence 5′-CACCT-3′ in different promoters. Represses transcription of E-cadherin. .

Involvement in disease

Mowat-Wilson syndrome (MOWS) [MIM:235730]: A complex developmental disorder characterized by mental retardation, delayed motor development, epilepsy, microcephaly and a wide spectrum of clinically heterogeneous features suggestive of neurocristopathies at the cephalic, cardiac, and vagal levels. Affected patients show an easily recognizable facial appearance with deep set eyes and hypertelorism, medially divergent, broad eyebrows, prominent columella, pointed chin and uplifted, notched ear lobes. Some patients manifest Hirschsprung disease. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the delta-EF1/ZFH-1 C2H2-type zinc-finger family.

Protein post-translational modifications

Sumoylation on Lys-391 and Lys-866 is promoted by the E3 SUMO-protein ligase CBX4, and impairs interaction with CTBP1 and transcription repression activity. .

Protein cellular localization

Nucleus .

Research area

All research areas>Transcription Regulators>ZEB2
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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