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Supplier : Arigo Biolaboratories
|Production type||ELISA Kits|
|Target Name||CCP antibody|
|Sample Type||Serum, Plasma|
|Sample Volume||10 ul|
|Full Name||cyclic citrullinated peptide Antibody|
|Alternate Names||Check alternative names for the Human CCP antibody ELISA Kit Expand|
|Assay Time||30, 15, 15, 5 min (RT)|
|Storage instruction||Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.|
|Note||Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.|
|User’s manual of Human CCP antibody ELISA Kit||Download|
|Cat No.|| |
|Sample type|| |
|Sample Volume|| |
|Target name|| |
|Assay time|| |
30, 15, 15, 5 min (RT)
|Store at|| |
4 Celcius degree
|Storage instruction|| |
Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Rheumatoid arthritis (RA) is one of the most common autoimmune diseases. It is characterized by a progressive inflammation of the joints, leading to gradual damage and loss of their function. Early diagnosis of RA and immediate onset of an appropriate treatment is essential for prevention of complete joint damage. It has been demonstrated in numerous studies that antibodies against citrullinated peptides from enolase, fibrinogen and especially vimentin occur in RA patients, and autoantibodies against cyclic citrullinated peptide (Anti-CCP) are sensitive and specific diagnostic markers for RA. They correlate with an erosive course of disease with severe joint damage and extraarticular manifestations. In addition to rheumatoid factors, autoantibodies against citrullinated peptides and proteins have proven to be valuable tools for the serological diagnosis of early RA. They have become a critical component of the 2010 ACR criteria for the classification of RA, and account for three of the six points required to verify a diagnosis of RA. Anti-CCP detects autoantibodies very early¨C sometimes even years before symptoms become evident. Persons without symptoms but with an increased Anti-CCP antibody titre are at high risk for future RA development. Furthermore, a positive result is predictive for a severe course of RA. Therefore, Anti-CCP is an effective tool for rapid and precise routine diagnosis and favours immediate implementation of treatment
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