Human CCP antibody ELISA Kit (ARG80377)

$699.00

Size: 96 wells
Conjugation:
Supplier: Arigo Biolaboratories

Overview


Supplier : Arigo Biolaboratories

 Production type ELISA Kits
Tested Reactivity Human
Tested Application ELISA
Specificity
Target Name CCP antibody
Conjugation
Conjugation Note
Sensitivity 1 U/ml
Detection Range
Sample Type Serum, Plasma
Sample Volume 10 ul
Precision

CV: <10%

Full Name cyclic citrullinated peptide Antibody
Alternate Names Check alternative names for the Human CCP antibody ELISA Kit

Expand


Application Instructions

 

Assay Time 30, 15, 15, 5 min (RT)


Properties

 

Form 96 wells
Storage instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.
Note Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.
User’s manual of Human CCP antibody ELISA Kit  Download
size

96 wells

Cat No.

ARG80377

Sensitivity

1 U/ml

Sample type

Serum, Plasma

Sample Volume

10 ul

Precision

CV: <10%

Target name

CCP antibody

Assay time

30, 15, 15, 5 min (RT)

Store at

4 Celcius degree

Storage instruction

Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.

Background

Rheumatoid arthritis (RA) is one of the most common autoimmune diseases. It is characterized by a progressive inflammation of the joints, leading to gradual damage and loss of their function. Early diagnosis of RA and immediate onset of an appropriate treatment is essential for prevention of complete joint damage. It has been demonstrated in numerous studies that antibodies against citrullinated peptides from enolase, fibrinogen and especially vimentin occur in RA patients, and autoantibodies against cyclic citrullinated peptide (Anti-CCP) are sensitive and specific diagnostic markers for RA. They correlate with an erosive course of disease with severe joint damage and extraarticular manifestations. In addition to rheumatoid factors, autoantibodies against citrullinated peptides and proteins have proven to be valuable tools for the serological diagnosis of early RA. They have become a critical component of the 2010 ACR criteria for the classification of RA, and account for three of the six points required to verify a diagnosis of RA. Anti-CCP detects autoantibodies very early¨C sometimes even years before symptoms become evident. Persons without symptoms but with an increased Anti-CCP antibody titre are at high risk for future RA development. Furthermore, a positive result is predictive for a severe course of RA. Therefore, Anti-CCP is an effective tool for rapid and precise routine diagnosis and favours immediate implementation of treatment

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!