Human Factor XIII ELISA Kit (ARG81134)

$729.00

Size: 96 wells
Conjugation: HRP
Supplier: Arigo Biolaboratories

Overview


Supplier : Arigo Biolaboratories

 Production type ELISA Kits
Tested Reactivity Human
Tested Application ELISA
Specificity
Target Name Human Factor XIII
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm
Sensitivity
Detection Range
Sample Type Serum, plasma, cell culture, urine, saliva, milk and CSF
Sample Volume 50 ul
Precision

CV: <10%

Full Name coagulation factor XIII, A1 polypeptide
Alternate Names Check alternative names for the Human Factor XIII ELISA Kit

Expand

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Application Instructions

 

Assay Time ~ 4 hours


Properties

 

Form 96 wells
Storage instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.
Note Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.
User’s manual of Human Factor XIII ELISA Kit  Download
size

96 wells

Cat No.

ARG81134

Conjugation note

Substrate: TMB and read at 450 nm

Sample type

Serum, plasma, cell culture, urine, saliva, milk and CSF

Sample Volume

50 ul

Precision

CV: <10%

Target name

Human Factor XIII

Assay time

~ 4 hours

Store at

4 Celcius degree

Storage instruction

Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.

Background

This gene encodes the coagulation factor XIII A subunit. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. This enzyme acts as a transglutaminase to catalyze the formation of gamma-glutamyl-epsilon-lysine crosslinking between fibrin molecules, thus stabilizing the fibrin clot. It also crosslinks alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin. Factor XIII deficiency is classified into two categories: type I deficiency, characterized by the lack of both the A and B subunits; and type II deficiency, characterized by the lack of the A subunit alone. These defects can result in a lifelong bleeding tendency, defective wound healing, and habitual abortion. [provided by RefSeq, Jul 2008]

Database link

All research areas>Signaling Intermediates>Coagulation Factor
(View all antibody categories related to Signaling Intermediates)

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