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Supplier : Arigo Biolaboratories
|Production type||ELISA Kits|
|Specificity||No significant cross-reactivity or interference with Human IL-2,4,7,9,15;mouse IL-2,4,15,21|
|Conjugation Note||Substrate: TMB and read at 450 nm|
|Detection Range||46.8-3000 pg/ml|
|Sample Type||Serum, Plasma, Cell culture supernatants|
|Sample Volume||100 ul|
|Full Name||interleukin 21|
|Alternate Names||Check alternative names for the Human IL21 ELISA Kit Expand
CVID11 Elisa kits|IL 21 Elisa kits|IL-21 Elisa kits|Il21 Elisa kits|IL21_HUMAN Elisa kits|Interleukin 21 Elisa kits|Interleukin-21 Elisa kits|interleukin-21 isoform Elisa kits|Interleukin21 Elisa kits|OTTHUMP00000164088 Elisa kits|Za11 Elisa kits
|Assay Time||4 hours|
|Storage instruction||Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.|
|Note||Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.|
|User’s manual of Human IL21 ELISA Kit||Download|
|Cat No.|| |
|Conjugation note|| |
Substrate: TMB and read at 450 nm
|Detection range|| |
|Sample type|| |
Serum, Plasma, Cell culture supernatants
|Sample Volume|| |
|Target name|| |
|Assay time|| |
|Store at|| |
4 Celcius degree
|Storage instruction|| |
Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Interleukin-21 (IL-21) is a secreted, type-I cytokine with immunoregulatory activity. Human IL-21 shares the common ange of lymphoid and myeloid cells of the immune system (T cells, B cells, natural killer (NK) cells and dendritic cells). IL21 is therefore is able to regulate innate and acquired immune responses. The biological effects of IL-21 include induction of differentiation, maturation, and proliferation of T-cells-stimulated B-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL-4 of IgG production, and induction of apoptotic effects in naive B-cells and stimulated B-cells in the absence of T-cell signaling. Human IL-21 has also been shown to promote the anti-tumor activity of CD8+ T-cells and NK cells. During T-cell mediated immune response, IL21 may inhibit dendritic cells¡¯ (DC) activation and maturation. In synergy with IL15 and IL18, IL21 stimulates interferon gamma production in T-cells and NK cells; with the IL15, it may play a role in proliferation and maturation of natural killer (NK) cells.
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