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Supplier : Arigo Biolaboratories
|Production type||ELISA Kits|
|Specificity||No significant cross-reactivity or interference with Human IFN-alphaA/D, IFN-alphaA, IFN-alphaB2, IFN-alphaG, IFN-alphaI, IFN-beta1a, IL-10 RbetaFc Chimera|
|Target Name||IL29 / IFN lambda|
|Conjugation Note||Substrate: TMB and read at 450 nm|
|Detection Range||31.25-2000 pg/ml|
|Sample Type||Serum, Plasma, Cell culture supernatants|
|Sample Volume||100 ul|
|Full Name||interferon, lambda 1|
|Alternate Names||Check alternative names for the Human IL29 / IFN lambda ELISA Kit Expand
Cytokine ZCYTO20 Elisa kits|IFN-lambda-2 Elisa kits|IFNL2 Elisa kits|IL-28A Elisa kits|IL28A Elisa kits|IL28A_HUMAN Elisa kits|Interferon lambda 2 Elisa kits|Interferon lambda-2 Elisa kits|interleukin 28A (interferon, lambda 2) Elisa kits|Interleukin 28A Elisa kits|Interleukin-28A Elisa kits|ZCYTO20 Elisa kits
|Assay Time||4 hours|
|Storage instruction||Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.|
|Note||Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.|
|User’s manual of Human IL29 / IFN lambda ELISA Kit||Download|
|Cat No.|| |
|Conjugation note|| |
Substrate: TMB and read at 450 nm
|Detection range|| |
|Sample type|| |
Serum, Plasma, Cell culture supernatants
|Sample Volume|| |
|Target name|| |
IL29 / IFN lambda
|Assay time|| |
|Store at|| |
4 Celcius degree
|Storage instruction|| |
Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
IL-29 is distantly related to type I interferons and the IL-10 family. Expression of IL-29 is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor beta (IL10RB) and interleukin 28 receptor alpha . IL-29 exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumour activity. IL-29 acts similarly to IFNs, but is less effective generally and has activity in a more limited range of cell lines. IL-29 produced in response to viral infection, activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection. IFN-Lambda 1 antiviral and antiproliferative activity requires Interferon-Lambda 2 receptor tyrosine residues. Recombinant human IL-29 produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 181 amino acids and having a molecular mass of?20 kDa.
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