Human Neuroserpin ELISA Kit (ARG80186)

$499.00

Size: 96 wells
Conjugation: HRP
Supplier: Arigo Biolaboratories

Overview


Supplier : Arigo Biolaboratories

 Production type ELISA Kits
Tested Reactivity Human
Tested Application ELISA
Specificity No significant cross-reactivity or interference with Human IL-2,3,4,5,6,7,9,10,12, IFN- gamma, TNF- alpha;mouse neuroserpin
Target Name Neuroserpin
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm
Sensitivity 30 pg/ml
Detection Range 62.5-4000 pg/ml
Sample Type Serum, Plasma, Cell culture supernatants
Sample Volume 100 ul
Precision

CV: <10%

Full Name serpin peptidase inhibitor, clade I (neuroserpin), member 1
Alternate Names Check alternative names for the Human Neuroserpin ELISA Kit

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DKFZp781N13156 Elisa kits|Neuroserpin Elisa kits|NEUS_HUMAN Elisa kits|Peptidase inhibitor 12 Elisa kits|PI-12 Elisa kits|PI12 Elisa kits|Protease inhibitor 12 Elisa kits|Serine or cysteine proteinase inhibitor clade I (neuroserpin) member 1 Elisa kits|Serine or cysteine proteinase inhibitor clade I member 1 Elisa kits|Serpin I1 Elisa kits|Serpin peptidase inhibitor clade I (neuroserpin) member 1 Elisa kits|SERPINI1 Elisa kits


Application Instructions

 

Assay Time 4 hours


Properties

 

Form 96 wells
Storage instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.
Note Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.
User’s manual of Human Neuroserpin ELISA Kit  Download
size

96 wells

Cat No.

ARG80186

Conjugation note

Substrate: TMB and read at 450 nm

Sensitivity

30 pg/ml

Detection range

62.5-4000 pg/ml

Sample type

Serum, Plasma, Cell culture supernatants

Sample Volume

100 ul

Precision

CV: <10%

Target name

Neuroserpin

Assay time

4 hours

Store at

4 Celcius degree

Storage instruction

Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.

Background

Neuroserpin is an inhibitory serpin that is expressed predominantly in central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggest that it plays an important role in controlling proteolytic degradation of extracellular matrix (ECM) during synaptogenesis and the subsequent development of neuronal plasticity. In the adult brain, neuroserpin is secreted from the growth cones of neurons in areas where synaptic changes are associated with learning and memory, i.e. cerebral cortex, hippocampus, and amygdala. The neuroprotective role of neuroserpin has been demonstrated in transgenic mice lacking neuroserpin expression. The deficiency of neuroserpin in these mice was associated with motor neuron disease characterized by axonal degradation. In humans, defects in neuroserpin, caused by point mutations in the neuroserpin gene, underlie a hereditary disorder called the familial encephalopathy with neuroserpin inclusion bodies (FENIB). Recombinant human neuroserpin is a 44.6 kDa non-glycosylated protein containing 394 amino-acid residues.

Database link

All research areas>Neurobiology Antibodies>neuroserpin
(View all antibody categories related to Neurobiology Antibodies)

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