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Supplier : Arigo Biolaboratories
|Production type||ELISA Kits|
|Target Name||Human PAI-1 uPA complex|
|Conjugation Note||TMB substrate is used for color development at 450 nm.|
|Detection Range||0.1 – 100 ng/ml|
|Sample Type||Plasma, serum, urine, cell culture media and tissue extracts|
|Full Name||plasminogen activator, urokinase|
|Alternate Names||Check alternative names for the Human PAI-1 uPA complex ELISA Kit Expand
ATF Elisa kits|BDPLT5 Elisa kits|EC 126.96.36.199 Elisa kits|PLAU Elisa kits|QPD Elisa kits|U plasminogen activator Elisa kits|u-PA Elisa kits|UPA Elisa kits|UPAM Elisa kits|Urinary plasminogen activator Elisa kits|URK Elisa kits|Urokinase plasminogen activator Elisa kits|Urokinase type plasminogen activator Elisa kits
|Storage instruction||Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.|
|Note||Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.|
|User’s manual of Human PAI-1 uPA complex ELISA Kit||Download|
|Cat No.|| |
|Conjugation note|| |
TMB substrate is used for color development at 450 nm.
|Detection range|| |
0.1 – 100 ng/ml
|Sample type|| |
Plasma, serum, urine, cell culture media and tissue extracts
|Target name|| |
Human PAI-1 uPA complex
|Store at|| |
4 Celcius degree
|Storage instruction|| |
Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer’s disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
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