Human PAI-1 uPA complex ELISA Kit (ARG81061)

$799.00

Size: 96 wells
Conjugation: HRP
Supplier: Arigo Biolaboratories

Overview


Supplier : Arigo Biolaboratories

 Production type ELISA Kits
Tested Reactivity Human
Tested Application ELISA
Specificity
Target Name Human PAI-1 uPA complex
Conjugation HRP
Conjugation Note TMB substrate is used for color development at 450 nm.
Sensitivity 0.07 ng/ml
Detection Range 0.1 – 100 ng/ml
Sample Type Plasma, serum, urine, cell culture media and tissue extracts
Sample Volume
Precision

CV: <10%

Full Name plasminogen activator, urokinase
Alternate Names Check alternative names for the Human PAI-1 uPA complex ELISA Kit

Expand

ATF Elisa kits|BDPLT5 Elisa kits|EC 3.4.21.73 Elisa kits|PLAU Elisa kits|QPD Elisa kits|U plasminogen activator Elisa kits|u-PA Elisa kits|UPA Elisa kits|UPAM Elisa kits|Urinary plasminogen activator Elisa kits|URK Elisa kits|Urokinase plasminogen activator Elisa kits|Urokinase type plasminogen activator Elisa kits


Application Instructions

 

Assay Time


Properties

 

Form 96 wells
Storage instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.
Note Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.
User’s manual of Human PAI-1 uPA complex ELISA Kit  Download
size

96 wells

Cat No.

ARG81061

Conjugation note

TMB substrate is used for color development at 450 nm.

Sensitivity

0.07 ng/ml

Detection range

0.1 – 100 ng/ml

Sample type

Plasma, serum, urine, cell culture media and tissue extracts

Precision

CV: <10%

Target name

Human PAI-1 uPA complex

Store at

4 Celcius degree

Storage instruction

Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.

Background

This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer’s disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

Database link

All research areas>Signaling Intermediates>uPA
(View all antibody categories related to Signaling Intermediates)

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