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Supplier : Arigo Biolaboratories
|Production type||ELISA Kits|
|Target Name||secretory IgA|
|Conjugation Note||Substrate: TMB and read at 450 nm|
|Sample Type||Saliva, Serum, urine, milk|
|Sample Volume||10 ul diluted|
|Full Name||secretory IgA|
|Alternate Names||Check alternative names for the Human secretory IgA ELISA Kit Expand|
|Assay Time||90, 30 min (37 Celcius degree), 15 min (RT)|
|Storage instruction||Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.|
|Note||Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.|
|User’s manual of Human secretory IgA ELISA Kit||Download|
|Cat No.|| |
|Conjugation note|| |
Substrate: TMB and read at 450 nm
|Sample type|| |
Saliva, Serum, urine, milk
|Sample Volume|| |
10 ul diluted
|Target name|| |
|Assay time|| |
90, 30 min (37 Celcius degree), 15 min (RT)
|Store at|| |
4 Celcius degree
|Storage instruction|| |
Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Secretory IgA (sIgA) is the main immunoglobulin present on mucosal surfaces. Ca. 90% of sIgA is produced locally and does not penetrate into blood circulation. sIgA is considerably different from serum IgA, as this complex protein consists of 3 completely different molecules. Two or four molecules of immunoglobulin A with molecular weight 160 kDa are joined by J-chain (16 kDa) and attached to the secretory component (80kDa); the formation of this complex occurs during transepithelial transport of polymeric IgA. sIgA plays a pivotal role in local immunity by blocking bacterial and viral adhesion and invasion through epithelial tissues. Determination of sIgA concentration allows to evaluate the local immunity status in stomatology, ophthalmology, respiratory diseases, gastroenterology, gynaecology. The sIgA in saliva can be also used as noninvasive mass screening for selective IgA deficiency. Elevation of sIgA in serum is occasionally observed in so autoimmune diseases and several tumours.
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