Human secretory IgA ELISA Kit (ARG80866)

$599.00

Size: 96 wells
Conjugation: HRP
Supplier: Arigo Biolaboratories

Overview


Supplier : Arigo Biolaboratories

 Production type ELISA Kits
Tested Reactivity Human
Tested Application ELISA
Specificity
Target Name secretory IgA
Conjugation HRP
Conjugation Note Substrate: TMB and read at 450 nm
Sensitivity 1 ?g/ml
Detection Range
Sample Type Saliva, Serum, urine, milk
Sample Volume 10 ul diluted
Precision

CV: <10%

Full Name secretory IgA
Alternate Names Check alternative names for the Human secretory IgA ELISA Kit

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Application Instructions

 

Assay Time 90, 30 min (37 Celcius degree), 15 min (RT)


Properties

 

Form 96 wells
Storage instruction Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.
Note Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.
User’s manual of Human secretory IgA ELISA Kit  Download
size

96 wells

Cat No.

ARG80866

Conjugation note

Substrate: TMB and read at 450 nm

Sensitivity

1 ?g/ml

Sample type

Saliva, Serum, urine, milk

Sample Volume

10 ul diluted

Precision

CV: <10%

Target name

secretory IgA

Assay time

90, 30 min (37 Celcius degree), 15 min (RT)

Store at

4 Celcius degree

Storage instruction

Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.

Background

Secretory IgA (sIgA) is the main immunoglobulin present on mucosal surfaces. Ca. 90% of sIgA is produced locally and does not penetrate into blood circulation. sIgA is considerably different from serum IgA, as this complex protein consists of 3 completely different molecules. Two or four molecules of immunoglobulin A with molecular weight 160 kDa are joined by J-chain (16 kDa) and attached to the secretory component (80kDa); the formation of this complex occurs during transepithelial transport of polymeric IgA. sIgA plays a pivotal role in local immunity by blocking bacterial and viral adhesion and invasion through epithelial tissues. Determination of sIgA concentration allows to evaluate the local immunity status in stomatology, ophthalmology, respiratory diseases, gastroenterology, gynaecology. The sIgA in saliva can be also used as noninvasive mass screening for selective IgA deficiency. Elevation of sIgA in serum is occasionally observed in so autoimmune diseases and several tumours.

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