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Supplier : Arigo Biolaboratories
|Production type||ELISA Kits|
|Specificity||No significant cross-reactivity or interference with Human IL-2,3,4,5,6,7,9,10,12, IFN- gamma, TNF- alpha|
|Target Name||sRANK Ligand / TNFSF11 / TRANCE|
|Conjugation Note||Substrate: TMB and read at 450 nm|
|Detection Range||15.6-1000 pg/ml|
|Sample Type||Serum, Plasma, Cell culture supernatants|
|Sample Volume||100 ul|
|Full Name||tumor necrosis factor (ligand) superfamily, member 11|
|Alternate Names||Check alternative names for the Human sRANK Ligand / TNFSF11 / TRANCE ELISA Kit Expand
CD254 Elisa kits|TNF11_HUMAN Elisa kits|TNFSF 11 Elisa kits|Tnfsf11 Elisa kits|TRANCE Elisa kits|Tumor necrosis factor (ligand) superfamily member 11 Elisa kits|Tumor necrosis factor ligand superfamily member 11 Elisa kits|Tumor necrosis factor ligand superfamily member 11, soluble form Elisa kits
|Assay Time||4 hours|
|Storage instruction||Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.|
|Note||Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.|
|User’s manual of Human sRANK Ligand / TNFSF11 / TRANCE ELISA Kit||Download|
|Cat No.|| |
|Conjugation note|| |
Substrate: TMB and read at 450 nm
|Detection range|| |
|Sample type|| |
Serum, Plasma, Cell culture supernatants
|Sample Volume|| |
|Target name|| |
sRANK Ligand / TNFSF11 / TRANCE
|Assay time|| |
|Store at|| |
4 Celcius degree
|Storage instruction|| |
Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
This gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell-dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss. This protein was shown to activate antiapoptotic kinase AKT/PKB through a signaling complex involving SRC kinase and tumor necrosis factor receptor-associated factor (TRAF) 6, which indicated this protein may have a role in the regulation of cell apoptosis. Targeted disruption of the related gene in mice led to severe osteopetrosis and a lack of osteoclasts. The deficient mice exhibited defects in early differentiation of T and B lymphocytes, and failed to form lobulo-alveolar mammary structures during pregnancy. Two alternatively spliced tra
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