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Supplier : Arigo Biolaboratories
|Production type||ELISA Kits|
|Target Name||Mouse Immunoglobulin M|
|Conjugation Note||TMB substrate is used for color development at 450 nm.|
|Detection Range||0.5 – 500 ng/ml|
|Sample Type||Serum, plasma, hybridoma cell supernatants and ascites|
|Full Name||immunoglobulin heavy constant mu|
|Alternate Names||Check alternative names for the Mouse Immunoglobulin M ELISA Kit Expand
heavy chain of IgM Elisa kits|Ig mu chain C region Elisa kits|Ig mu chain C region secreted form Elisa kits|Igh 6 Elisa kits|Igh-6 Elisa kits|IGHM Elisa kits|Igm Elisa kits|immunoglobulin heavy chain Elisa kits
|Storage instruction||Store the kit at 2-8°C. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components or simply ask Antibodyplus for ELISA troublesooting.|
|Note||Antibodyplus and Arigo provide the most validated ELISA kits for researchers. For laboratory research only, not for drug, diagnostic or other use.|
|User’s manual of Mouse Immunoglobulin M ELISA Kit||Download|
|Cat No.|| |
|Conjugation note|| |
TMB substrate is used for color development at 450 nm.
|Detection range|| |
0.5 – 500 ng/ml
|Sample type|| |
Serum, plasma, hybridoma cell supernatants and ascites
|Target name|| |
Mouse Immunoglobulin M
|Store at|| |
4 Celcius degree
|Storage instruction|| |
Store the kit at 2-8 Celcius degree. Keep microplate wells sealed in a dry bag with desiccants. Do not expose test reagents to heat, sun or strong light during storage and usage. Please refer to the product user manual for detail temperatures of the components.
Immunoglobulins (Ig) are the antigen recognition molecules of B cells. An Ig molecule is made up of 2 identical heavy chains and 2 identical light chains (see MIM 147200) joined by disulfide bonds so that each heavy chain is linked to a light chain and the 2 heavy chains are linked together. Each Ig heavy chain has an N-terminal variable (V) region containing the antigen-binding site and a C-terminal constant (C) region, encoded by an individual C region gene, that determines the isotype of the antibody and provides effector or signaling functions. The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070), joining (J) genes (see MIM 147010), and diversity (D) genes (see MIM 146910). The C region genes are clustered downstream of the V region genes within the heavy chain locus on chromosome 14. The IGHM gene encodes the C region of the mu heavy chain, which defines the IgM isotype. Naive B cells express the transmembrane forms of IgM and IgD (see IGHD; MIM 1471770) on their surface. During an antibody response, activated B cells can switch to the expression of individual downstream heavy chain C region genes by a process of somatic recombination known as isotype switching. In addition, secreted Ig forms that act as antibodies can be produced by alternative RNA processing of the heavy chain C region sequences. Although the membrane forms of all Ig isotypes are monomeric, secreted IgM forms pentamers, and occasionally hexamers, in plasma (summary by Janeway et al., 2005).[supplied by OMIM, Aug 2010]
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