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Mouse Monoclonal ABCG2 antibody [1H2] (STJ97810)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IF, ELISA
Recommended dilution: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
ABCG2 antibody, ABCP antibody, BCRP antibody, BCRP1 antibody, MXR antibody,|ABC transporter antibody|ABC15 antibody|ABCG 2 antibody|ABCG2 antibody|ABCG2_HUMAN antibody|ABCP antibody|ATP binding cassette sub family G (WHITE) member 2 antibody|ATP binding cassette transporter G2 antibody|ATP-binding cassette sub-family G member 2 antibody|BCRP antibody|BCRP1 antibody|BMDP antibody|Breast cancer resistance protein antibody|CD338 antibody|CDw338 antibody|CDw338 antigen antibody|EST157481 antibody|GOUT1 antibody|MGC102821 antibody|Mitoxantrone resistance associated protein antibody|Mitoxantrone resistance-associated protein antibody|MRX antibody|Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2 antibody|MXR antibody|MXR1 antibody|Placenta specific ATP binding cassette transporter antibody|Placenta specific MDR protein antibody|Placenta-specific ATP-binding cassette transporter antibody|UAQTL1 antibody|Anti-BCRP/ABCG2 antibody [BXP-53] (ab24115)
SCBT cat No: sc-25156|sc-25821|
ABCG2 Monoclonal Antibody
|Catalogue No.|| |
Human, Mouse, Monkey
ABCG2 Monoclonal Antibody detects endogenous levels of ABCG2 protein.
Purified recombinant fragment of human ABCG2 expressed in E Coli
WB, IF, ELISA
|Recommended dilution|| |
WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:10000
ABCG2 Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.
ABCG2 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
ATP-binding cassette sub-family G member 2 antibody, Breast cancer resistance protein antibody, CDw338 antibody, Mitoxantrone resistance-associated protein antibody, Placenta-specific ATP-binding cassette transporter antibody, Urate exporter antibody, CD antigen CD338 antibody
|Protein names|| |
ATP-binding cassette sub-family G member 2 , Breast cancer resistance protein , CDw338 , Mitoxantrone resistance-associated protein , Placenta-specific ATP-binding cassette transporter , Urate exporter , CD antigen CD338
|Protein function|| |
High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.
|Protein tissue specificity|| |
Highly expressed in placenta. Low expression in small intestine, liver and colon.
|Protein sequence and domain|| |
The extracellular loop 3 (ECL3) is involved in binding porphyrins and transfer them to other carriers, probably albumin. / Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily. [View classification] / Contains 1 ABC transmembrane type-2 domain. / Contains 1 ABC transporter domain.
|Protein post-translational modifications|| |
Glycosylation-deficient ABCG2 is normally expressed and functional.
|Protein cellular localization|| |
Cell membrane / Multi-pass membrane protein / Mitochondrion membrane / Multi-pass membrane protein
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St John’s Laboratory Ltd.
|Product type|| |
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