Mouse Monoclonal Actin beta antibody (KLH) [8H10D10] (STJ97814)


Reactivity: Human, Mouse, Rat, Hamster, Monkey
Applications: WB, IF, FC, ELISA
Conjugation: KLH
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Actin beta antibody (KLH) [8H10D10] (STJ97814)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IF, FC, ELISA

Recommended dilution: WB 1:500-1:2000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


ACTB antibody,|A26C1A antibody|A26C1B antibody|ACTB antibody|ACTB_HUMAN antibody|Actin cytoplasmic 1 antibody|Actin, cytoplasmic 1, N-terminally processed antibody|Actx antibody|b actin antibody|Beta cytoskeletal actin antibody|Beta-actin antibody|BRWS1 antibody|E430023M04Rik antibody|MGC128179 antibody|PS1TP5 binding protein 1 antibody|PS1TP5BP1 antibody|Anti-beta Actin antibody [mAbcam 8224] – Loading Control (ab8224)
SCBT cat No: sc-56499|sc-166524|sc-7454|sc-17829|sc-15335|sc-7453|sc-135819|sc-393495|



Actin beta Monoclonal Antibody

Catalogue No.



Human, Mouse, Rat, Hamster, Monkey


Actin beta Monoclonal Antibody detects endogenous levels of Actin beta protein.


Synthetic peptide corresponding to amino-terminal residues of human Actin beta, conjugated to KLH





Recommended dilution

WB 1:500-1:2000; IF 1:200-1:1000; FC 1:200-1:400; ELISA 1:10000








Actin beta Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.


1 mg/ml


Actin beta Antibody was purified using affinity purification.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Actin, cytoplasmic 1 antibody, Beta-actin antibody

Database links

Human UniProt/Swiss-Prot:P60709;Mouse UniPort/Swiss-Prot: P60710;Rat UniProt/Swiss-Port: P60711;Human Entrez Gene: 60;Mouse Entrez Gene: 11461;Rat Entrez Gene: Rn.94978

Protein names

Actin, cytoplasmic 1 , Beta-actin

Protein function

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Involvement in disease

Dystonia, juvenile-onset (DJO) [MIM:607371]: A form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. Patients with juvenile-onset dystonia manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Baraitser-Winter syndrome 1 (BRWS1) [MIM:243310]: A rare developmental disorder characterized by the combination of congenital ptosis, high-arched eyebrows, hypertelorism, ocular colobomata, and a brain malformation consisting of anterior-predominant lissencephaly. Other typical features include postnatal short stature and microcephaly, intellectual disability, seizures, and hearing loss. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the actin family.

Protein post-translational modifications

ISGylated. / Oxidation of Met-44 and Met-47 by MICALs (MICAL1, MICAL2 or MICAL3) to form methionine sulfoxide promotes actin filament depolymerization. MICAL1 and MICAL2 produce the (R)-S-oxide form. The (R)-S-oxide form is reverted by MSRB1 and MSRB2, which promote actin repolymerization (By similarity). / Monomethylation at Lys-84 (K84me1) regulates actin-myosin interaction and actomyosin-dependent processes. Demethylation by ALKBH4 is required for maintaining actomyosin dynamics supporting normal cleavage furrow ingression during cytokinesis and cell migration. / (Microbial infection) Monomeric actin is cross-linked by V.cholerae toxins RtxA and VgrG1 in case of infection: bacterial toxins mediate the cross-link between Lys-50 of one monomer and Glu-270 of another actin monomer, resulting in formation of highly toxic actin oligomers that cause cell rounding . The toxin can be highly efficient at very low concentrations by acting on formin homology family proteins: toxic actin oligomers bind with high affinity to formins and adversely affect both nucleation and elongation abilities of formins, causing their potent inhibition in both profilin-dependent and independent manners .

Protein cellular localization

Cytoplasm > cytoskeleton

Research area

All research areas>Structural Proteins>Actin
(View all antibody categories related to Structural Proteins)


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St John’s Laboratory Ltd.

Product type

Primary antibody


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