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Mouse Monoclonal Actinin-alpha2 antibody (STJ98460)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, IF
Recommended dilution: WB 1:1000-1:2000; IF 1:100-1:500
Recommended protocols: check protocols
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Check alternative names for the antibodyExpand
ACTN2 antibody,|Actin binding protein antibody|CLABP antibody|Clipin A antibody|Clipin-A antibody|CLIPINA antibody|COR1A_HUMAN antibody|CORO1A antibody|Coronin 1 antibody|Coronin actin binding protein 1A antibody|Coronin like protein A antibody|Coronin like protein p57 antibody|Coronin-1A antibody|Coronin-like protein A antibody|Coronin-like protein p57 antibody|FLJ41407 antibody|HCORO1 antibody|MGC117380 antibody|OTTHUMP00000163017 antibody|p57 antibody|TACO antibody|Tryptophan aspartate containing coat protein antibody|Tryptophan aspartate-containing coat protein antibody|Anti-Sarcomeric Alpha Actinin antibody [EA-53] (ab9465)
SCBT cat No: To be updated
Actinin-alpha2 Monoclonal Antibody
|Catalogue No.|| |
Human, Rat, Cow, Chicken, Dog, Pig, Zebrafish
Actinin-alpha2 Monoclonal Antibody detects endogenous levels of Actinin-alpha2 protein.
Purified recombinant human Actinin-alpha2 (C-terminus) protein fragments expressed in Ecoli
|Recommended dilution|| |
WB 1:1000-1:2000; IF 1:100-1:500
Actinin-alpha2 Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Actinin-alpha2 Antibody was purified using affinity purification.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Alpha-actinin-2 antibody, Alpha-actinin skeletal muscle isoform 2 antibody, F-actin cross-linking protein antibody
|Protein names|| |
Alpha-actinin-2 , Alpha-actinin skeletal muscle isoform 2 , F-actin cross-linking protein
|Protein function|| |
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
|Protein tissue specificity|| |
Expressed in both skeletal and cardiac muscle.
|Involvement in disease|| |
Cardiomyopathy, familial hypertrophic 23, with or without left ventricular non-compaction (CMH23) [MIM:612158]: A hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Cardiomyopathy, dilated 1AA, with or without left ventricular non-compaction (CMD1AA) [MIM:612158]: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. . Note: The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the alpha-actinin family. / Contains 1 actin-binding domain. / Contains 2 CH (calponin-homology) domains. / Contains 2 EF-hand domains. / Contains 4 spectrin repeats.
|Protein post-translational modifications|| |
Ubiquitinated by FBXL22, leading to proteasomal degradation.
|Protein cellular localization|| |
Cytoplasm > myofibril > sarcomere > Z line
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St John’s Laboratory Ltd.
|Product type|| |
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