Mouse Monoclonal Actinin-alpha2 antibody (STJ98460)

$379.00

Reactivity: Human, Rat, Cow, Chicken, Dog, Pig, Zebrafish
Applications: WB, IF
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Actinin-alpha2 antibody (STJ98460)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IF

Recommended dilution: WB 1:1000-1:2000; IF 1:100-1:500

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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ACTN2 antibody,|Actin binding protein antibody|CLABP antibody|Clipin A antibody|Clipin-A antibody|CLIPINA antibody|COR1A_HUMAN antibody|CORO1A antibody|Coronin 1 antibody|Coronin actin binding protein 1A antibody|Coronin like protein A antibody|Coronin like protein p57 antibody|Coronin-1A antibody|Coronin-like protein A antibody|Coronin-like protein p57 antibody|FLJ41407 antibody|HCORO1 antibody|MGC117380 antibody|OTTHUMP00000163017 antibody|p57 antibody|TACO antibody|Tryptophan aspartate containing coat protein antibody|Tryptophan aspartate-containing coat protein antibody|Anti-Sarcomeric Alpha Actinin antibody [EA-53] (ab9465)
SCBT cat No: To be updated

 

Name

Actinin-alpha2 Monoclonal Antibody

Catalogue No.

STJ98460

Reactivity

Human, Rat, Cow, Chicken, Dog, Pig, Zebrafish

Specificity

Actinin-alpha2 Monoclonal Antibody detects endogenous levels of Actinin-alpha2 protein.

Immunogen

Purified recombinant human Actinin-alpha2 (C-terminus) protein fragments expressed in Ecoli

Host

Mouse

Applications

WB, IF

Recommended dilution

WB 1:1000-1:2000; IF 1:100-1:500

Clonality

Monoclonal

Conjugation

Unconjugated

Formulation

Actinin-alpha2 Antibody was tube-contained. Purified in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Concentration

1 mg/ml

Purification

Actinin-alpha2 Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Alpha-actinin-2 antibody, Alpha-actinin skeletal muscle isoform 2 antibody, F-actin cross-linking protein antibody

Database links

Human UniProt/Swiss-Prot:P35609;Mouse UniPort/Swiss-Prot: Q9JI91;Rat UniProt/Swiss-Port: D3ZCV0;Human Entrez Gene: 88;Mouse Entrez Gene: 11472;Rat Entrez Gene: Rn.3970

Protein names

Alpha-actinin-2 , Alpha-actinin skeletal muscle isoform 2 , F-actin cross-linking protein

Protein function

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

Protein tissue specificity

Expressed in both skeletal and cardiac muscle.

Involvement in disease

Cardiomyopathy, familial hypertrophic 23, with or without left ventricular non-compaction (CMH23) [MIM:612158]: A hereditary heart disorder characterized by ventricular hypertrophy, which is usually asymmetric and often involves the interventricular septum. The symptoms include dyspnea, syncope, collapse, palpitations, and chest pain. They can be readily provoked by exercise. The disorder has inter- and intrafamilial variability ranging from benign to malignant forms with high risk of cardiac failure and sudden cardiac death. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Cardiomyopathy, dilated 1AA, with or without left ventricular non-compaction (CMD1AA) [MIM:612158]: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the alpha-actinin family. / Contains 1 actin-binding domain. / Contains 2 CH (calponin-homology) domains. / Contains 2 EF-hand domains. / Contains 4 spectrin repeats.

Protein post-translational modifications

Ubiquitinated by FBXL22, leading to proteasomal degradation.

Protein cellular localization

Cytoplasm > myofibril > sarcomere > Z line

Research area

All research areas>Cell Adhesion Proteins>Actinin
(View all antibody categories related to Cell Adhesion Proteins)

Note

AntibodyPlus can customize Actinin-alpha2 Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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