Mouse Monoclonal AMACR antibody [2A10F3] (STJ97825)

$379.00

Reactivity: Human, Mouse
Applications: WB, IHC, IF, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal AMACR antibody [2A10F3] (STJ97825)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, IHC, IF, ELISA

Recommended dilution: WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000

Recommended protocols: check protocols

Image descriptions:

Click or hover above images to see image description for AMACR Monoclonal Antibody.

Alternative names:

Check alternative names for the antibody

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AMACR antibody,|2 methylacyl CoA racemase antibody|2-methylacyl-CoA racemase antibody|Alpha methylacyl CoA racemase antibody|Alpha-methylacyl-CoA racemase antibody|Amacr antibody|AMACR_HUMAN antibody|AMACRD antibody|CBAS4 antibody|EC 5.1.99.4 antibody|Macr1 antibody|RACE antibody|RM antibody|Anti-AMCR antibody (ab175280)
SCBT cat No: sc-136022|sc-81710|sc-514408|sc-514424|

 

Name

AMACR Monoclonal Antibody

Catalogue No.

STJ97825

Reactivity

Human, Mouse

Specificity

AMACR Monoclonal Antibody detects endogenous levels of AMACR protein.

Immunogen

Purified recombinant fragment of human AMACR expressed in E Coli

Host

Mouse

Applications

WB, IHC, IF, ELISA

Recommended dilution

WB 1:500-1:2000; IHC 1:200-1:1000; IF 1:200-1:1000; ELISA 1:10000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2b

Formulation

AMACR Antibody was tube-contained. Ascitic fluid containing 0.03% sodium azide.

Concentration

1 mg/ml

Purification

AMACR Antibody was purified using affinity purification.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

Alpha-methylacyl-CoA racemase antibody, 2-methylacyl-CoA racemase antibody

Database links

Human UniProt/Swiss-Prot:Q9UHK6;Mouse UniPort/Swiss-Prot: O09174;Rat UniProt/Swiss-Port: G3V8F9;Human Entrez Gene: 23600;Mouse Entrez Gene: 17117;Rat Entrez Gene: Rn.2590

Protein names

Alpha-methylacyl-CoA racemase , 2-methylacyl-CoA racemase

Protein function

Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers. / (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA. / /

Involvement in disease

Alpha-methylacyl-CoA racemase deficiency (AMACRD) [MIM:614307]: A rare autosomal recessive peroxisomal disorder characterized by elevated plasma concentrations of pristanic acid C27-bile-acid intermediates, and adult onset of variable neurodegenerative symptoms affecting the central and peripheral nervous systems. Features may include seizures, visual failure, sensorimotor neuropathy, spasticity, migraine, and white matter hyperintensities on brain imaging. . Note: The disease is caused by mutations affecting the gene represented in this entry.; Congenital bile acid synthesis defect 4 (CBAS4) [MIM:214950]: A disorder characterized by the presence of trihydroxycoprostanic acid in the bile and absence of cholic acid. Patients manifest neonatal jaundice, intrahepatic cholestasis and bile duct deficiency. . Note: The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the CaiB/BaiF CoA-transferase family.

Protein cellular localization

Peroxisome / Mitochondrion

Note

AntibodyPlus can customize AMACR Antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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