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Mouse Monoclonal Anti-AMPKbeta 1 antibody (STJ99185)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-AMPKbeta 1 antibody.
Check alternative names for the antibodyExpand
|1300015D22Rik antibody|5”-AMP-activated protein kinase subunit beta-1 antibody|AAKB1_HUMAN antibody|AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1 antibody|AMP-activated, noncatalytic, beta-1 antibody|AMPK antibody|AMPK beta 1 chain antibody|AMPK subunit beta-1 antibody|AMPK-BETA-1 antibody|AMPKb antibody|AU021155 antibody|E430008F22 antibody|HAMPKb antibody|MGC17785 antibody|PRKAB1 antibody|Protein kinase AMP activated non catalytic subunit beta 1 antibody|Anti-AMPK beta 1 antibody [Y367] (ab32112)
SCBT cat No: sc-19133|sc-20163|sc-19132|sc-100357|sc-100358|sc-376752|
Anti-AMPKbeta 1 antibody
|Catalogue No.|| |
Human, Mouse, Rat, Monkey
Anti-AMPKbeta 1 antibody detects endogenous levels of AMPK beta 1 and does not cross-react with related proteins.
Purified recombinant human AMPK beta 1 protein fragments expressed in E.coli.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-AMPKbeta 1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-AMPKbeta 1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
1300015D22Rik antibody, 5''-AMP-activated protein kinase subunit beta-1 antibody, AAKB1_HUMAN antibody, AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1 antibody, AMP-activated, noncatalytic, beta-1 antibody, AMPK antibody, AMPK beta 1 chain antibody, AMPK subunit beta-1 antibody, AMPK-BETA-1 antibody, AMPKb antibody, AU021155 antibody, E430008F22 antibody, HAMPKb antibody, MGC17785 antibody, PRKAB1 antibody, Protein kinase AMP activated non catalytic subunit beta 1 antibody
|Database links|| |
|Protein function|| |
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
|Protein sequence and domain|| |
Belongs to the 5'-AMP-activated protein kinase beta subunit family. The glycogen-binding domain may target AMPK to glycogen so that other factors like glycogen-bound debranching enzyme or protein phosphatases can directly affect AMPK activity.
|Protein post-translational modifications|| |
Phosphorylated when associated with the catalytic subunit (PRKAA1 or PRKAA2). Phosphorylated by ULK1; leading to negatively regulate AMPK activity and suggesting the existence of a regulatory feedback loop between ULK1 and AMPK. .
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Kinases-and-Phosphatases/">Kinases and Phosphatases</a>><a href="http://antibodyplus.com/product-tag/AMPK/">AMPK</a><br><a href="http://antibodyplus.com/product-tag/Kinases-and-Phosphatases/"> (View all antibody categories related to Kinases and Phosphatases)</a>
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St John’s Laboratory Ltd.
|Product type|| |
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