Mouse Monoclonal Anti-ATP-Citrate Lyase antibody (STJ99082)

$99.00$319.00

Reactivity: Human, Mouse, Monkey
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-ATP-Citrate Lyase antibody (STJ99082)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|ACL antibody|Acly antibody|ACLY_HUMAN antibody|ATP citrate (pro-S) lyase antibody|ATP citrate lyase antibody|ATP citrate synthase antibody|ATP-citrate (pro-S-)-lyase antibody|ATP-citrate synthase antibody|ATPcitrate synthase antibody|ATPCL antibody|Citrate cleavage enzyme antibody|CLATP antibody|OTTHUMP00000164773 antibody|Anti-ATP citrate lyase antibody [EP704Y] (ab40793)
SCBT cat No: sc-30538|sc-30537|sc-368656|sc-241869|sc-271614|

Name

Anti-ATP-Citrate Lyase antibody

Catalogue No.

STJ99082

Reactivity

Human, Mouse, Monkey

Specificity

Anti-ATP-Citrate Lyase antibody detects endogenous levels of ATP-Citrate Lyase and does not cross-react with related proteins.

Immunogen

Purified recombinant human ATP-Citrate Lyase protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2a

Molecular weight

120kDa

Formulation

Anti-ATP-Citrate Lyase antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-ATP-Citrate Lyase antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

ACL antibody, Acly antibody, ACLY_HUMAN antibody, ATP citrate (pro-S) lyase antibody, ATP citrate lyase antibody, ATP citrate synthase antibody, ATP-citrate (pro-S-)-lyase antibody, ATP-citrate synthase antibody, ATPcitrate synthase antibody, ATPCL antibody, Citrate cleavage enzyme antibody, CLATP antibody, OTTHUMP00000164773 antibody

Database links

UniProt/Swiss-Prot:P53396

Protein function

ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine. .

Protein sequence and domain

In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. ; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. ; Contains 1 ATP-grasp domain.

Protein post-translational modifications

ISGylated. .; Acetylated at Lys-540, Lys-546 and Lys-554 by KAT2B/PCAF. Acetylation is promoted by glucose and stabilizes the protein, probably by preventing ubiquitination at the same sites. Acetylation promotes de novo lipid synthesis. Deacetylated by SIRT2. .; Ubiquitinated at Lys-540, Lys-546 and Lys-554 by UBR4, leading to its degradation. Ubiquitination is probably inhibited by acetylation at same site (Probable). .

Protein cellular localization

Cytoplasm.

Research area

All research areas>Synthesis and Degradation>Citrate synthase
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize Anti-ATP-Citrate Lyase antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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