No products in the cart.
Mouse Monoclonal Anti-Bag1 antibody (STJ99243)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Bag1 antibody.
Check alternative names for the antibodyExpand
|Bag 1 antibody|BAG family molecular chaperone regulator 1 antibody|BAG-1 antibody|BAG1 antibody|BAG1_HUMAN antibody|BCL 2 Associated Athanogene 1 antibody|BCL 2 associated athanogene antibody|BCL 2 binding athanogene 1 antibody|Bcl-2-associated athanogene 1 antibody|BCL2 associated athanogene 1 antibody|BCL2 associated athanogene antibody|Glucocorticoid receptor-associated protein RAP46 antibody|HAP1 antibody|Haptoglobin antibody|RAP 46 antibody|RAP46 antibody|Anti-Bag1 antibody [Y166] (ab32109)
SCBT cat No: sc-135844|sc-56003|sc-56004|sc-377419|sc-515535|sc-939|sc-33704|sc-376848|sc-515529|sc-377454|sc-25296|sc-8348|sc-56005|
|Catalogue No.|| |
Purified recombinant human Bag1 protein fragments expressed in E.coli.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-Bag1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Bag1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
Bag 1 antibody, BAG family molecular chaperone regulator 1 antibody, BAG-1 antibody, BAG1 antibody, BAG1_HUMAN antibody, BCL 2 Associated Athanogene 1 antibody, BCL 2 associated athanogene antibody, BCL 2 binding athanogene 1 antibody, Bcl-2-associated athanogene 1 antibody, BCL2 associated athanogene 1 antibody, BCL2 associated athanogene antibody, Glucocorticoid receptor-associated protein RAP46 antibody, HAP1 antibody, Haptoglobin antibody, RAP 46 antibody, RAP46 antibody
|Database links|| |
|Protein function|| |
Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 induced by various stimuli. .
|Protein tissue specificity|| |
Isoform 4 is the most abundantly expressed isoform. It is ubiquitously expressed throughout most tissues, except the liver, colon, breast and uterine myometrium. Isoform 1 is expressed in the ovary and testis. Isoform 4 is expressed in several types of tumor cell lines, and at consistently high levels in leukemia and lymphoma cell lines. Isoform 1 is expressed in the prostate, breast and leukemia cell lines. Isoform 3 is the least abundant isoform in tumor cell lines (at protein level). .
|Protein sequence and domain|| |
Contains 1 BAG domain. ; Contains 1 ubiquitin-like domain.
|Protein post-translational modifications|| |
Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation. .
|Protein cellular localization|| |
Isoform 1: Nucleus. Cytoplasm. Note=Isoform 1 localizes predominantly to the nucleus.; Isoform 2: Cytoplasm. Nucleus. Note=Isoform 2 localizes to the cytoplasm and shuttles into the nucleus in response to heat shock.; Isoform 4: Cytoplasm. Nucleus. Note=Isoform 4 localizes predominantly to the cytoplasm. The cellular background in which it is expressed can influence whether it resides primarily in the cytoplasm or is also found in the nucleus. In the presence of BCL2, localizes to intracellular membranes (what appears to be the nuclear envelope and perinuclear membranes) as well as punctate cytosolic structures suggestive of mitochondria.
AntibodyPlus can customize Anti-Bag1 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: