Mouse Monoclonal Anti-Caspase-9 antibody (STJ99219)


Reactivity: Human, Transfected
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-Caspase-9 antibody (STJ99219)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody


|APAF-3 antibody|Apoptotic protease Mch-6 antibody|Caspase 9 Dominant Negative antibody|Caspase 9c antibody|Caspase-9 antibody|Caspase-9 subunit p10 antibody|ICE LAP6 antibody|ICE like apoptotic protease 6 antibody|ICE-LAP6 antibody|ICE-like apoptotic protease 6 antibody|MCH6 antibody|PPP1R56 antibody|protein phosphatase 1, regulatory subunit 56 antibody|RNCASP9 antibody|Anti-Caspase-9 antibody [E23] (ab32539)
SCBT cat No: sc-81650|sc-56073|sc-70505|sc-70506|sc-70507|sc-56076|sc-81663|sc-81589|sc-73548|sc-56077|sc-8297|sc-17784|sc-7885|sc-133109|sc-8355|sc-374489|sc-373777|


Anti-Caspase-9 antibody

Catalogue No.



Human, Transfected


Anti-Caspase-9 antibody detects endogenous levels of Caspase-9 and does not cross-react with related proteins.


Purified recombinant human Caspase-9 protein fragments expressed in E.coli.











Molecular weight



Anti-Caspase-9 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.


1 mg/ml


Anti-Caspase-9 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.


-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

APAF-3 antibody, Apoptotic protease Mch-6 antibody, Caspase 9 Dominant Negative antibody, Caspase 9c antibody, Caspase-9 antibody, Caspase-9 subunit p10 antibody, ICE LAP6 antibody, ICE like apoptotic protease 6 antibody, ICE-LAP6 antibody, ICE-like apoptotic protease 6 antibody, MCH6 antibody, PPP1R56 antibody, protein phosphatase 1, regulatory subunit 56 antibody, RNCASP9 antibody

Protein function

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).; Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

Protein tissue specificity

Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes. .

Protein sequence and domain

Belongs to the peptidase C14A family. ; Contains 1 CARD domain.

Protein post-translational modifications

Cleavages at Asp-315 by granzyme B and at Asp-330 by caspase-3 generate the two active subunits. Caspase-8 and -10 can also be involved in these processing events.; Phosphorylated at Thr-125 by MAPK1/ERK2. Phosphorylation at Thr-125 is sufficient to block caspase-9 processing and subsequent caspase-3 activation. Phosphorylation on Tyr-153 by ABL1/c-Abl; occurs in the response of cells to DNA damage. .

Research area

<a href="">All research areas</a>><a href="">Tumor Suppressor/Apoptosis</a>><a href="">Caspase</a><br><a href=""&gt; (View all antibody categories related to Tumor Suppressor/Apoptosis)</a>


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St John’s Laboratory Ltd.

Product type

Primary antibody


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