Mouse Monoclonal Anti-Cytochrome P450 17A1 antibody (STJ99161)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-Cytochrome P450 17A1 antibody (STJ99161)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|20 lyase antibody|CP17A_HUMAN antibody|CPT7 antibody|CYP17 antibody|CYP17A1 antibody|CYPXVII antibody|Cytochrome P450 17A1 antibody|Cytochrome P450 family 17 antibody|Cytochrome P450 family 17 subfamily A polypeptide 1 antibody|Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia antibody|Cytochrome p450 XVIIA1 antibody|Cytochrome P450-C17 antibody|Cytochrome P450c17 antibody|OTTHUMP00000020382 antibody|P450 C17 antibody|P450c17 antibody|S17AH antibody|Steroid 17 alpha hydroxylase/17,20 lyase antibody|Steroid 17 alpha monooxygenase antibody|Steroid 17-alpha-hydroxylase/17 antibody|Steroid 17-alpha-monooxygenase antibody|Anti-Cytochrome P450 17A1 antibody [EPR6293] (ab125022)
SCBT cat No: sc-374244|sc-376711|sc-66849|sc-66850|sc-46084|sc-46085|

Name

Anti-Cytochrome P450 17A1 antibody

Catalogue No.

STJ99161

Reactivity

Human

Specificity

Anti-Cytochrome P450 17A1 antibody detects endogenous levels of Cytochrome P450 17A1 and does not cross-react with related proteins.

Immunogen

Purified recombinant human Cytochrome P450 17A1 protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2b

Molecular weight

60kDa

Formulation

Anti-Cytochrome P450 17A1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-Cytochrome P450 17A1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

20 lyase antibody, CP17A_HUMAN antibody, CPT7 antibody, CYP17 antibody, CYP17A1 antibody, CYPXVII antibody, Cytochrome P450 17A1 antibody, Cytochrome P450 family 17 antibody, Cytochrome P450 family 17 subfamily A polypeptide 1 antibody, Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia antibody, Cytochrome p450 XVIIA1 antibody, Cytochrome P450-C17 antibody, Cytochrome P450c17 antibody, OTTHUMP00000020382 antibody, P450 C17 antibody, P450c17 antibody, S17AH antibody, Steroid 17 alpha hydroxylase/17,20 lyase antibody, Steroid 17 alpha monooxygenase antibody, Steroid 17-alpha-hydroxylase/17 antibody, Steroid 17-alpha-monooxygenase antibody

Database links

UniProt/Swiss-Prot:P05093

Protein function

Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. .

Involvement in disease

Adrenal hyperplasia 5 (AH5) [MIM:202110]: A form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. Congenital adrenal hyperplasia is characterized by androgen excess leading to ambiguous genitalia in affected females, rapid somatic growth during childhood in both sexes with premature closure of the epiphyses and short adult stature. Four clinical types: ‘salt wasting’ (SW, the most severe type), ‘simple virilizing’ (SV, less severely affected patients), with normal aldosterone biosynthesis, ‘non-classic form’ or late-onset (NC or LOAH)and ‘cryptic’ (asymptomatic). . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the cytochrome P450 family.

Protein post-translational modifications

Phosphorylation is necessary for 17,20-lyase, but not for 17-alpha-hydroxylase activity. .

Protein cellular localization

Membrane .

Research area

All research areas>Synthesis and Degradation>CYP
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus can customize Anti-Cytochrome P450 17A1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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