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Mouse Monoclonal Anti-Cytochrome P450 17A1 antibody (STJ99161)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-Cytochrome P450 17A1 antibody.
Check alternative names for the antibodyExpand
|20 lyase antibody|CP17A_HUMAN antibody|CPT7 antibody|CYP17 antibody|CYP17A1 antibody|CYPXVII antibody|Cytochrome P450 17A1 antibody|Cytochrome P450 family 17 antibody|Cytochrome P450 family 17 subfamily A polypeptide 1 antibody|Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia antibody|Cytochrome p450 XVIIA1 antibody|Cytochrome P450-C17 antibody|Cytochrome P450c17 antibody|OTTHUMP00000020382 antibody|P450 C17 antibody|P450c17 antibody|S17AH antibody|Steroid 17 alpha hydroxylase/17,20 lyase antibody|Steroid 17 alpha monooxygenase antibody|Steroid 17-alpha-hydroxylase/17 antibody|Steroid 17-alpha-monooxygenase antibody|Anti-Cytochrome P450 17A1 antibody [EPR6293] (ab125022)
SCBT cat No: sc-374244|sc-376711|sc-66849|sc-66850|sc-46084|sc-46085|
Anti-Cytochrome P450 17A1 antibody
|Catalogue No.|| |
Anti-Cytochrome P450 17A1 antibody detects endogenous levels of Cytochrome P450 17A1 and does not cross-react with related proteins.
Purified recombinant human Cytochrome P450 17A1 protein fragments expressed in E.coli.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-Cytochrome P450 17A1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-Cytochrome P450 17A1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
20 lyase antibody, CP17A_HUMAN antibody, CPT7 antibody, CYP17 antibody, CYP17A1 antibody, CYPXVII antibody, Cytochrome P450 17A1 antibody, Cytochrome P450 family 17 antibody, Cytochrome P450 family 17 subfamily A polypeptide 1 antibody, Cytochrome p450 subfamily XVII (steroid 17 alpha hydroxylase) adrenal hyperplasia antibody, Cytochrome p450 XVIIA1 antibody, Cytochrome P450-C17 antibody, Cytochrome P450c17 antibody, OTTHUMP00000020382 antibody, P450 C17 antibody, P450c17 antibody, S17AH antibody, Steroid 17 alpha hydroxylase/17,20 lyase antibody, Steroid 17 alpha monooxygenase antibody, Steroid 17-alpha-hydroxylase/17 antibody, Steroid 17-alpha-monooxygenase antibody
|Database links|| |
|Protein function|| |
Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty. .
|Involvement in disease|| |
Adrenal hyperplasia 5 (AH5) [MIM:202110]: A form of congenital adrenal hyperplasia, a common recessive disease due to defective synthesis of cortisol. Congenital adrenal hyperplasia is characterized by androgen excess leading to ambiguous genitalia in affected females, rapid somatic growth during childhood in both sexes with premature closure of the epiphyses and short adult stature. Four clinical types: ‘salt wasting’ (SW, the most severe type), ‘simple virilizing’ (SV, less severely affected patients), with normal aldosterone biosynthesis, ‘non-classic form’ or late-onset (NC or LOAH)and ‘cryptic’ (asymptomatic). . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the cytochrome P450 family.
|Protein post-translational modifications|| |
Phosphorylation is necessary for 17,20-lyase, but not for 17-alpha-hydroxylase activity. .
|Protein cellular localization|| |
AntibodyPlus can customize Anti-Cytochrome P450 17A1 antibody according to your requirement, including bulk product size,etc. Please contact email@example.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.
St John’s Laboratory Ltd.
|Product type|| |
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