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Mouse Monoclonal Anti-EIF4EBP3 antibody (STJ99277)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-EIF4EBP3 antibody.
Check alternative names for the antibodyExpand
|4EBP1 antibody|4EBP2 antibody|4EBP3 antibody|eIF4E binding protein 1 antibody|eIF4E binding protein 2 antibody|eIF4E binding protein 3 antibody|Eukaryotic translation initiation factor 4E binding protein 1 antibody|Eukaryotic translation initiation factor 4E binding protein 2 antibody|Eukaryotic translation initiation factor 4E binding protein 3 antibody|PHAS1 antibody|Phospho anti-eIF4EBP1 + eIF4EBP2 + eIF4EBP3 (T45) antibody [EPR2169Y] (ab68187)
SCBT cat No: sc-134232|
|Catalogue No.|| |
Recombinant protein of human EIF4EBP3.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-EIF4EBP3 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-EIF4EBP3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
4EBP1 antibody, 4EBP2 antibody, 4EBP3 antibody, eIF4E binding protein 1 antibody, eIF4E binding protein 2 antibody, eIF4E binding protein 3 antibody, Eukaryotic translation initiation factor 4E binding protein 1 antibody, Eukaryotic translation initiation factor 4E binding protein 2 antibody, Eukaryotic translation initiation factor 4E binding protein 3 antibody, PHAS1 antibody
|Database links|| |
|Protein function|| |
Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. .
|Protein tissue specificity|| |
Expression is highest in skeletal muscle, heart, kidney, and pancreas, whereas there is very little expression in brain and thymus. .
|Protein sequence and domain|| |
Belongs to the eIF4E-binding protein family.
|Protein post-translational modifications|| |
|Research area|| |
<a href="http://antibodyplus.com/research-areas/">All research areas</a>><a href="http://antibodyplus.com/Signaling-Intermediates/">Signaling Intermediates</a>><a href="http://antibodyplus.com/product-tag/4E-BP/">4E-BP</a><br><a href="http://antibodyplus.com/product-tag/Signaling-Intermediates/"> (View all antibody categories related to Signaling Intermediates)</a>
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St John’s Laboratory Ltd.
|Product type|| |
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