Mouse Monoclonal Anti-ERCC1 antibody (STJ99240)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-ERCC1 antibody (STJ99240)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|COFS 4 antibody|COFS4 antibody|DNA excision repair protein ERCC 1 antibody|DNA excision repair protein ERCC-1 antibody|DNA excision repair protein ERCC1 antibody|ERCC 1 antibody|ERCC1 antibody|ERCC1_HUMAN antibody|Excision repair cross complementation group 1 antibody|Excision repair cross complementing 1 antibody|Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody|Excision repair protein antibody|RAD 10 antibody|RAD10 antibody|UV 20 antibody|UV20 antibody|Anti-ERCC1 antibody [8F1] (ab2356)
SCBT cat No: sc-53281|sc-56673|sc-515258|sc-17809|sc-10157|sc-10785|sc-56386|

Name

Anti-ERCC1 antibody

Catalogue No.

STJ99240

Reactivity

Human

Specificity

Anti-ERCC1 antibody detects endogenous levels of ERCC1 and does not cross-react with related proteins.

Immunogen

Purified recombinant human ERCC1 protein fragments expressed in E.coli.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2b

Molecular weight

39kDa

Formulation

Anti-ERCC1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-ERCC1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

COFS 4 antibody, COFS4 antibody, DNA excision repair protein ERCC 1 antibody, DNA excision repair protein ERCC-1 antibody, DNA excision repair protein ERCC1 antibody, ERCC 1 antibody, ERCC1 antibody, ERCC1_HUMAN antibody, Excision repair cross complementation group 1 antibody, Excision repair cross complementing 1 antibody, Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody, Excision repair protein antibody, RAD 10 antibody, RAD10 antibody, UV 20 antibody, UV20 antibody

Database links

UniProt/Swiss-Prot:P07992

Protein function

Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.

Involvement in disease

Cerebro-oculo-facio-skeletal syndrome 4 (COFS4) [MIM:610758]: A disorder of prenatal onset characterized by microcephaly, congenital cataracts, facial dysmorphism, neurogenic arthrogryposis, growth failure and severe psychomotor retardation. COFS is considered to be part of the nucleotide-excision repair disorders spectrum that include also xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the ERCC1/RAD10/SWI10 family.

Protein cellular localization

Isoform 1: Nucleus.; Isoform 2: Cytoplasm. Nucleus.; Isoform 3: Nucleus.; Isoform 4: Nucleus.

Research area

All research areas>Transcription Regulators>ERCC1
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus can customize Anti-ERCC1 antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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