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Mouse Monoclonal Anti-ERCC1 antibody (STJ99240)
Supplier: St John’s Laboratory Ltd.
Recommended applications: WB, ELISA
Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000
Recommended protocols: check protocols
Click or hover above images to see image description for Anti-ERCC1 antibody.
Check alternative names for the antibodyExpand
|COFS 4 antibody|COFS4 antibody|DNA excision repair protein ERCC 1 antibody|DNA excision repair protein ERCC-1 antibody|DNA excision repair protein ERCC1 antibody|ERCC 1 antibody|ERCC1 antibody|ERCC1_HUMAN antibody|Excision repair cross complementation group 1 antibody|Excision repair cross complementing 1 antibody|Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody|Excision repair protein antibody|RAD 10 antibody|RAD10 antibody|UV 20 antibody|UV20 antibody|Anti-ERCC1 antibody [8F1] (ab2356)
SCBT cat No: sc-53281|sc-56673|sc-515258|sc-17809|sc-10157|sc-10785|sc-56386|
|Catalogue No.|| |
Anti-ERCC1 antibody detects endogenous levels of ERCC1 and does not cross-react with related proteins.
Purified recombinant human ERCC1 protein fragments expressed in E.coli.
|Recommended dilution|| |
WB 1:500-2000; ELISA 1:10000-20000
|Molecular weight|| |
Anti-ERCC1 antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Anti-ERCC1 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-20 Celsius degree. Avoid repeated freeze/thaw cycles.
|Alternative antibody names|| |
COFS 4 antibody, COFS4 antibody, DNA excision repair protein ERCC 1 antibody, DNA excision repair protein ERCC-1 antibody, DNA excision repair protein ERCC1 antibody, ERCC 1 antibody, ERCC1 antibody, ERCC1_HUMAN antibody, Excision repair cross complementation group 1 antibody, Excision repair cross complementing 1 antibody, Excision Repair Cross Complementing Rodent Repair Deficiency Complementation Group 1 antibody, Excision repair protein antibody, RAD 10 antibody, RAD10 antibody, UV 20 antibody, UV20 antibody
|Database links|| |
|Protein function|| |
Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5′-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
|Involvement in disease|| |
Cerebro-oculo-facio-skeletal syndrome 4 (COFS4) [MIM:610758]: A disorder of prenatal onset characterized by microcephaly, congenital cataracts, facial dysmorphism, neurogenic arthrogryposis, growth failure and severe psychomotor retardation. COFS is considered to be part of the nucleotide-excision repair disorders spectrum that include also xeroderma pigmentosum, trichothiodystrophy and Cockayne syndrome. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the ERCC1/RAD10/SWI10 family.
|Protein cellular localization|| |
Isoform 1: Nucleus.; Isoform 2: Cytoplasm. Nucleus.; Isoform 3: Nucleus.; Isoform 4: Nucleus.
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St John’s Laboratory Ltd.
|Product type|| |
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