Mouse Monoclonal Anti-FADD antibody (STJ99183)

$99.00$319.00

Reactivity: Human
Applications: WB, ELISA
Conjugation: Unconjugated
Supplier: St John’s Laboratory Ltd.

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Mouse Monoclonal Anti-FADD antibody (STJ99183)

Supplier: St John’s Laboratory Ltd.

Recommended applications: WB, ELISA

Recommended dilution: WB 1:500-2000; ELISA 1:10000-20000

Recommended protocols: check protocols

Image descriptions:

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Alternative names:

Check alternative names for the antibody

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|FADD antibody|FADD protein antibody|FADD_HUMAN antibody|Fas (TNFRSF6) associated via death domain antibody|Fas associated via death domain antibody|Fas associating death domain containing protein antibody|Fas associating protein antibody|Fas associating protein with death domain antibody|Fas TNFRSF6 associated via death domain antibody|FAS-associated death domain protein antibody|FAS-associating death domain-containing protein antibody|GIG 3 antibody|GIG3 antibody|Growth inhibiting gene 3 protein antibody|Growth-inhibiting gene 3 protein antibody|H sapiens mRNA for mediator of receptor induced toxicity antibody|Mediator of receptor induced toxicity antibody|MGC8528 antibody|MORT 1 antibody|MORT1 antibody|Protein FADD antibody|Anti-FADD antibody (ab24533)
SCBT cat No: sc-271748|sc-134337|sc-292676|

Name

Anti-FADD antibody

Catalogue No.

STJ99183

Reactivity

Human

Specificity

Anti-FADD antibody detects endogenous levels of FADD and does not cross-react with related proteins.

Immunogen

Recombinant human FADD protein.

Host

Mouse

Applications

WB, ELISA

Recommended dilution

WB 1:500-2000; ELISA 1:10000-20000

Clonality

Monoclonal

Conjugation

Unconjugated

Isotype

IgG2a

Molecular weight

28kDa

Formulation

Anti-FADD antibody was tube-contained in liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration

1 mg/ml

Purification

Anti-FADD antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-20 Celsius degree. Avoid repeated freeze/thaw cycles.

Alternative antibody names

FADD antibody, FADD protein antibody, FADD_HUMAN antibody, Fas (TNFRSF6) associated via death domain antibody, Fas associated via death domain antibody, Fas associating death domain containing protein antibody, Fas associating protein antibody, Fas associating protein with death domain antibody, Fas TNFRSF6 associated via death domain antibody, FAS-associated death domain protein antibody, FAS-associating death domain-containing protein antibody, GIG 3 antibody, GIG3 antibody, Growth inhibiting gene 3 protein antibody, Growth-inhibiting gene 3 protein antibody, H sapiens mRNA for mediator of receptor induced toxicity antibody, Mediator of receptor induced toxicity antibody, MGC8528 antibody, MORT 1 antibody, MORT1 antibody, Protein FADD antibody

Database links

UniProt/Swiss-Prot:Q13158

Protein function

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. .

Protein tissue specificity

Expressed in a wide variety of tissues, except for peripheral blood mononuclear leukocytes.

Involvement in disease

Infections, recurrent, associated with encephalopathy, hepatic dysfunction and cardiovascular malformations (IEHDCM) [MIM:613759]: A condition with biological features of autoimmune lymphoproliferative syndrome such as high-circulating CD4(-)CD8(-)TCR-alpha-beta(+) T-cell counts, and elevated IL10 and FASL levels. Affected individuals suffer from recurrent, stereotypical episodes of fever, encephalopathy, and mild liver dysfunction sometimes accompanied by generalized seizures. The episodes can be triggered by varicella zoster virus (VZV), measles mumps rubella (MMR) attenuated vaccine, parainfluenza virus, and Epstein-Barr virus (EBV). . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains 1 death domain. ; Contains 1 DED (death effector) domain. Contains a death domain involved in the binding of the corresponding domain within Fas receptor. ; The interaction between the FAS and FADD death domains is crucial for the formation of the death-inducing signaling complex (DISC).

Research area

All research areas>Tumor Suppressor/Apoptosis>FADD
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus can customize Anti-FADD antibody according to your requirement, including bulk product size,etc. Please contact info@antibodyplus.com. AntibodyPlus provide antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

St John’s Laboratory Ltd.

Product type

Primary antibody

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